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3-Methyl-L-histidine

SIGMA/M9005

Synonym: π-Methyl-L-histidine; 1-Methyl-L-histidine (archaic); 3-(1-Methylimidazol-5-yl)-L-alanine

CAS Number: 368-16-1
Empirical Formula (Hill Notation): C7H11N3O2
Molecular Weight: 169.18
EC Number: 206-704-6
MDL Number: MFCD00083658
Linear Formula: C7H11N3O2
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-M9005-100MG 100 mg
$135.00
1/EA
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45-M9005-250MG 250 mg
$321.00
1/EA
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45-M9005-1G 1 g
$1270.00
1/EA
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This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.

This image depicts SKU: M9005-100MG

 

application(s) detection
assay ≥98% (TLC)
color white to off-white
form powder
InChI 1S/C7H11N3O2/c1-10-4-9-3-5(10)2-6(8)7(11)12/h3-4,6H,2,8H2,1H3,(H,11,12)/t6-/m0/s1
InChI key JDHILDINMRGULE-LURJTMIESA-N
mp 254 °C
Quality Level 100 
SMILES string Cn1cncc1C[C@H](N)C(O)=O
Application:

  • Engineering mutually orthogonal PylRS/tRNA pairs for dual encoding of functional histidine analogues.: Exploring innovative genetic engineering techniques, this research advances the use of histidine analogues like 3-Methyl-L-histidine for producing novel proteins with enhanced functionalities, offering vast potential in therapeutic and industrial applications (Taylor et al., 2023 ).

  • Improving the enzymatic activity of l-amino acid α-ligase for imidazole dipeptide production by site-directed mutagenesis.: This investigation enhances the enzymatic synthesis of imidazole dipeptides, crucial for understanding the role of modifications like those seen in 3-Methyl-L-histidine and its impact on biological activities (Kino et al., 2023 ).

Biochem/physiol Actions: 3-Methyl-L-histidine is a non-proteinogenic amino acid and an index of muscle breakdown.
Packaging: 100 mg in poly bottle
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (TLC)
mp 254 °C
UNSPSC 12352209

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