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Mecamylamine hydrochloride

SIGMA/M9020

Synonym: 2-(Methylamino)isocamphane hydrochloride; Inversine; N,2,3,3-Tetramethylbicyclo[2.2.1]heptan-2-amine hydrochloride

CAS Number: 826-39-1
Empirical Formula (Hill Notation): C11H21N · HCl
Molecular Weight: 203.75
EC Number: 212-555-8
MDL Number: MFCD00151462
Linear Formula: C11H21N · HCl
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-M9020-5MG 5 mg
 $72.60
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45-M9020-25MG 25 mg
 $282.00
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45-M9020-100MG 100 mg
 $842.00
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This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: M9020-100MG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: M9020-25MG

 

form powder
InChI 1S/C11H21N.ClH/c1-10(2)8-5-6-9(7-8)11(10,3)12-4;/h8-9,12H,5-7H2,1-4H3;1H/t8-,9+,11?;/m1./s1
InChI key PKVZBNCYEICAQP-CIISUUNXSA-N
originator AstraZeneca
Quality Level 200 
SMILES string Cl.[H][C@@]12CC[C@@]([H])(C1)C(C)(NC)C2(C)C
solubility ethanol: 122 mg/mL
  glycerol: 95 mg/mL
  H2O: 47 mg/mL
  isopropanol: 476 mg/mL
Application: Mecamylamine hydrochloride has been used as an additive in extracellular saline during current-clamp recordings to reduce synaptic input. It has also been used as a non-selective nicotinic acetyl choline receptor blocker in aortic body neurons and in MLO-Y4 cells.
Biochem/physiol Actions: Noncompetitive nicotinic acetylcholine receptor antagonist; preferentially blocks nicotinic receptors at autonomic ganglia; crosses blood-brain barrier.
Disclaimer: Solutions are stable to autoclaving.
Features and Benefits: This compound is featured on the Acetylcholine Receptors (Nicotinic)  page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
Features and Benefits: This compound was developed by AstraZeneca . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here .
Packaging: 5, 25, 100 mg in glass bottle
UNSPSC 12352116

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