Microsomes from Liver, Pooled
SIGMA/M9191 - from rat(Sprague-Dawley), female
Synonym: lab equipment accessory
Product Type: Chemical
| biological source | rat (Sprague-Dawley) |
| form | liquid |
| packaging | vial of ~10 mg |
| Quality Level | 200  |
| shipped in | dry ice |
| specific activity | ≥20 units/mg protein, pH 7.4, 37 °C |
| storage temp. | −70°C |
| Biochem/physiol Actions: | Liver microsomes are subcellular particles derived from the endoplasmic reticulum of hepatic cells. These microsomes are a rich source of drug metabolizing enzymes, including cytochrome P-450. Microsome pools from various sources are useful in the study of xenobiotic metabolism and drug interactions. |
| Biochem/physiol Actions: | Source of drug metabolizing enzymes, including cytochrome P-450. |
| Other Notes: | One unit will reduce 1 nanomole of cytochrome C per minute at pH 7.4 at 37 deg C. 7-ethoxyresorufin O-deethylase activity: One unit will hydroxylate 1.0 picomole paclitaxel per minute at pH 7.4 at 37 deg C. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| activity | specific activity: ≥20 units/mg protein, pH 7.4, 37 °C |
| Storage Temp. | −70°C |
| UNSPSC | 12161501 |