Memantine hydrochloride

SIGMA/M9292 - ≥98% (GC)

Synonym: 3,5-Dimethyl-1-adamantanamine hydrochloride; 3,5-Dimethylamantadine hydrochloride; 3,5-Dimethyltricyclo[3.3.1.1^3,7]decan-1-amine hydrochloride

CAS Number: 41100-52-1
Empirical Formula (Hill Notation): C₁₂H₂₁N · HCl
Molecular Weight: 215.76
EC Number: 255-219-6
MDL Number: MFCD00214336
Linear Formula: C₁₂H₂₁N · HCl
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-M9292-25MG	25 mg	$83.30 1/EA	Add To Favorites
45-M9292-100MG	100 mg	$257.00 1/EA	Add To Favorites

This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: M9292-100MG

Properties
Descriptions
Safety Info.
Basic Data

assay	≥98% (GC)
form	powder
InChI	1S/C12H21N.ClH/c1-10-3-9-4-11(2,6-10)8-12(13,5-9)7-10;/h9H,3-8,13H2,1-2H3;1H/t9-,10+,11-,12-;
InChI key	LDDHMLJTFXJGPI-VXMZOEJHSA-N
originator	Forest Labs
Quality Level	100
SMILES string	Cl.C[C@]12CC3C[C@](C)(C1)CC(N)(C3)C2

Application:	Memantine hydrochloride has been used: • as a media supplement to serve as a control to study the neuroprotective effects of erythropoietin in N-methyl-D-aspartate receptor-induced toxicity • to intraperitoneally inject experimental animal to study its effect on traumatic injury • as a test compound to determine the dynamic range and selectivity of retinal pigment epithelium tissue penetration
Biochem/physiol Actions:	Low-affinity NMDA glutamate receptor antagonist; stimulates dopamine release.
Biochem/physiol Actions:	Memantine is effective against Alzheimer′s disease and Parkinson′s disease. It is also useful in treating epilepsy, motor neurone disease and trauma.
Features and Benefits:	This compound is a featured product for ADME Tox and Neuroscience research. Discover more featured ADME Tox and Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm .
Features and Benefits:	This compound is featured on the Glutamate Receptors (Ion Channel Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
Features and Benefits:	This compound was developed by Forest Labs . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here .
Packaging:	100 mg in glass bottle
Packaging:	25 mg in glass insert

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98% (GC)
UNSPSC	12352200

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