Menadione
SIGMA/M9429 - meets USP testing specifications
Synonym: 2-
CAS Number: 58-27-5
Empirical Formula (Hill Notation): C11H8O2
Molecular Weight: 172.18
EC Number: 200-372-6
MDL Number: MFCD00001681
Linear Formula: C11H8O2
Product Type: Chemical
| agency | meets USP testing specifications |
| USP/NF | |
| application(s) | pharmaceutical (small molecule) |
| assay | 98.5-101.0% dry basis |
| biological source | synthetic (organic) |
| form | solid |
| InChI | 1S/C11H8O2/c1-7-6-10(12)8 |
| InChI key | MJVAVZPDRWSRRC-UHFFFAOYSA |
| mp | 105-107 °C (lit.) |
| Quality Level | 200 ![]() |
| SMILES string | CC1=CC(=O)c2ccccc2C1=O |
| Application: | Menadione has been used: • to treat HL-60 cells as positive control for apoptosis for flow cytometry • as an oxidative stress inducer in transgenic embryos after 24 h of post fertilization • to treat HaCaT cell line, for quantifying total and oxidised glutathione |
| Biochem/physiol Actions: | Menadione is an oxidative stress inducer. |
| General description: | Menadione (Vitamin K3) is the synthetic form of vitamin K. It has the structure similar to vitamin K1 and K2. Vitamin K1, K2 and K3 are biologically active. Water soluble forms of menadiones are used in swine and poultry diets. |
| Packaging: | 25, 100 g in glass bottle |
| Symbol | ![]() ![]() GHS07,GHS08,GHS09 |
| Signal word | Danger |
| Hazard statements | H302 - H315 - H319 - H334 - H335 - H410 |
| Precautionary statements | P261 - P264 - P273 - P301 + P312 - P302 + P352 - P305 + P351 + P338 |
| Hazard Codes | Xn |
| Risk Statements | 22-36/37/38 |
| Safety Statements | 26-36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Purity | 98.5-101.0% dry basis |
| mp | 105-107 °C (lit.) |
| UNSPSC | 12352205 |




