Monoclonal Anti-Myelin Basic Protein (MBP) (36-50) antibody produced in rat
SIGMA/M9434 - clone 14, tissue culture supernatant
Synonym: Anti-MBP
MDL Number: MFCD01324037
Product Type: Chemical
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| antibody form | tissue culture supernatant |
| antibody product type | primary antibodies |
| biological source | rat |
| clone | 14, monoclonal |
| conjugate | unconjugated |
| contains | 0.09% sodium azide |
| isotype | IgG |
| Quality Level | 200  |
| shipped in | dry ice |
| species reactivity | horse, chicken, human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | ELISA: suitable |
| immunofluorescence: suitable | |
| immunohistochemistry: suitable | |
| UniProt accession no. | P02686  |
| Biochem/physiol Actions: | Myelin basic protein (MBP) associates with calmodulin and has been identified as an auto-antigen in multiple sclerosis (MS). It also inhibits the assembly of amyloid-β protein. |
| Biochem/physiol Actions: | Recognizes amino acids 36-50 of myelin basic protein. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | Myelin basic protein (MBP) is part of the myelin sheath and is a calcium-dependent protein. It has six isoforms and the gene encoding it is localized on human chromosome 18q23. |
| Immunogen: | bovine myelin basic protein. |
| Preparation Note: | Generated by somatic cell hybridization of NS0 myeloma cells with spleen cells from an outbred rat immunized with bovine myelin basic protein. |
| Hazard Codes | Xn |
| Risk Statements | 22 |
| RIDADR | NONH for all modes of transport |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |