Mannan−Agarose
SIGMA/M9917 - saline suspension
Synonym: Mannan Binding Protein Agarose
MDL Number: MFCD00213010
Product Type: Chemical
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| biological source | plant |
| capacity | ≥30 mg/mL binding capacity (concanavalin A) |
| form | saline suspension |
| matrix | cross-linked 4% beaded agarose |
| matrix activation | cyanogen bromide |
| matrix attachment | hydroxyl |
| matrix spacer | 1 atom |
| Quality Level | 200  |
| storage temp. | 2-8°C |
| suitability | suitable for chromatography |
| technique(s) | affinity chromatography: suitable |
| Application: | Mannan-agarose is used in protein chromatography, affinity chromatography and carbohydrate matrices. Mannan-agarose has been used in studies assessing poly(ADP-ribosyl)ation of mannose-binding lectin out of human kidney cells and to inform mannose-associated serine protease (MASP) activated components of the coagulation system. Mannan-agarose has also been used to study the innate immunity and resistance to Aeromonas salmonicida exhibited by the sea lamprey (Petromyzon marinus), a parasitic cartilaginous fish of the North American Great Lakes and a predator of many bony fish species of commercial importance to the fishing industry. Mannan-Agarose has been used to deplete rabbit anti-mannose-binding lectin (MBL) polyclonal antiserum of anti-mannan antibodies. |
| Packaging: | 25 mL in glass bottle |
| Physical form: | Suspension in 1.0 M NaCl, 10 mM imidazole containing preservative |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Storage Temp. | 2-8°C |
| UNSPSC | 23151817 |