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Phenylalanine Assay Kit

SIGMA/MAK005 - sufficient for 100 fluorometric tests

Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-MAK005-1KT 1 kit
 $584.00
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Photo is meant to be representative of packaging you will receive if ordered. Appropriate product information is printed on actual labels and package types are subject to change.
Phenylalanine Assay Kit, standard curve.

 

detection method fluorometric
relevant disease(s) neonatal diseases; neurological disorders; pediatric diseases
storage temp. −20°C
usage sufficient for 100 fluorometric tests
Application: Suitable for L-phenylalanine detection in cell and tissue culture supernatants, serum, and other biological samples
Biochem/physiol Actions: Phenylalanine concentration is determined by a coupled enzyme assay, which results in the deamination of phenylalanine and the production of NADH which reacts with the probe resulting in a fluorescent (λex = 535 nm/λem = 587 nm) product, proportional to the phenylalanine present.
General description: Phenylalanine is a non-polar essential amino acid. In the liver, phenylalanine is converted to tyrosine, which is a precursor for multiple compounds including L-DOPA and melanin. Defects in the activity of phenylalanine hydroxylase result in the inherited metabolic disorder phenylketonuria (PKU). PKU results in the build up of phenylalanine and phenylalanine metabolites, and can result in growth defects and mental retardation if not treated.
RIDADR NONH for all modes of transport
Storage Temp. −20°C
UNSPSC 12161503

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