Lipid Peroxidation (MDA) Assay Kit
SIGMA/MAK085 - sufficient for 100 colorimetric or fluorometric tests
Synonym: MDA Assay; TBARS Assay; Thiobarbituric Acid Reactive Substances Assay
Product Type: Chemical
| detection method | colorimetric |
| fluorometric | |
| drug control | regulated under CDSA - not available from Sigma-Aldrich Canada |
| input | tissue |
| relevant disease(s) | endocrinological disorders, diabetes; neurological disorders; cancer; cardiovascular diseases |
| species reactivity | mouse |
| storage condition | dry at room temperature |
| storage temp. | −20°C |
| technique(s) | activity assay: suitable |
| usage | sufficient for 100 colorimetric or fluor |
| Application: | Lipid peroxidation (MDA) assay kit has been used to determine the levels of malondialdehyde (MDA). |
| Application: | Suitable for the measurement of malondialdehyde (MDA) in a variety of samples including tissue, cells and plasma |
| Biochem/physiol Actions: | In this kit, lipid peroxidation is determined by the reaction of MDA with thiobarbituric acid (TBA) to form a colorimetric (532 nm)/fluorometric (λex = 532/λem = 553 nm) product, proportional to the MDA present. |
| General description: | Lipid peroxidation is the degradation of lipids that occurs as a result of oxidative damage and is a useful marker for oxidative stress. Polyunsaturated lipids are susceptible to an oxidative attack, typically by reactive oxygen species, resulting in a well-defined chain reaction with the production of end products such as malondialdehyde (MDA). Lipid peroxidation may contribute to the pathology of many diseases including atherosclerosis, diabetes, and Alzheimer′s. |
| Symbol |     GHS02,GHS05,GHS07,GHS09 |
| Signal word | Danger |
| Hazard statements | H225 - H302 - H314 - H411 |
| Precautionary statements | P210 - P273 - P280 - P301 + P312 - P303 + P361 + P353 - P305 + P351 + P338 |
| Hazard Codes | F,C |
| Risk Statements | 11-22-34-52/53 |
| Safety Statements | 16-26-36/37/39-45-61 |
| RIDADR | UN 3316 9 |
| WGK Germany | WGK 3 |
| Flash Point(F) | 57.2 °F - closed cup |
| Flash Point(C) | 14 °C - closed cup |
| Storage Temp. | −20°C |
| UNSPSC | 12161503 |