CETP Activity Assay Kit
SIGMA/MAK106 - Supplied by Roar Biomedical, Inc.
Synonym: Cholesteryl ester transfer protein activity assay kit
Product Type: Chemical
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CETP activity in human plasma.
Inhibition of CETP with TP2 mAb.
Torcetrapib titration into CETP activity Assay.
| application(s) | pharmaceutical |
| detection method | fluorometric |
| relevant disease(s) | cardiovascular diseases |
| storage temp. | 2-8°C |
| usage | sufficient for 100 fluorometric tests |
| Analysis Note: | Learn more about Roar Assay Kits for Studies in Lipoprotein Metabolism.  |
| Application: | Cholesteryl ester transfer protein (CETP) activity Assay Kit has been used for measurement of CETP activity in the plasma samples. |
| Application: | Suitable for the detection of cholesteryl ester transfer protein (CETP) in plasma / serum (fresh or frozen), recombinant or purified CETP. |
| Biochem/physiol Actions: | The CETP Activity Assay Kit uses a proprietary substrate that enables the detection of CETP-mediated transfer of neutral lipid from the substrate to a physiological acceptor. The transfer activity results in an increase in fluorescence intensity (λEx=535 nm/λEm=587 nm). In a total volume of 200 μL, the assay is linear from 0.2 to 0.8 μL of normal human plasma. Assay results not affected by endogenous plasma HDL, LDL or VLDL concentrations. |
| Features and Benefits: | Compatible with high-throughput handling systems. |
| General description: | Cholesteryl ester transfer protein (CETP) is present in normal human plasma. The protein transfers neutral lipids from high density lipoproteins (HDL) to very low density lipoprotein (VLDL) and low density lipoprotein (LDL). CETP plays an important role in lipoprotein metabolism and influences the reverse cholesterol transport pathway. The method is useful for measuring CETP activity in plasma or serum in all species that express CETP. |
| RIDADR | NONH for all modes of transport |
| Storage Temp. | 2-8°C |
| UNSPSC | 12161503 |