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Sialic Acid Assay Kit

SIGMA/MAK314 - sufficient for 100 colorimetric or fluorometric tests

Synonym: Sialic Acid (NANA) Assay Kit

Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-MAK314-1KT 1 kit
 $611.00
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detection method colorimetric
  fluorometric
relevant disease(s) cancer; cardiovascular diseases; hematological disorder
storage temp. −20°C
usage sufficient for 100 colorimetric or fluorometric tests
Application:

  • Evaluation of serum total sialic acid in moderate COVID-19 patients with and without gastrointestinal tract manifestations.: The study measures serum sialic acid levels in COVID-19 patients to understand the disease′s impact on the gastrointestinal tract (Haroun et al., 2022 ).
Application: Suitable for the quantitative determination of free and total sialic acid (NANA) and evaluation of drug effects on sialic acid in serum, plasma, saliva, milk etc.
Biochem/physiol Actions: This sialic acid assay uses an improved Warren method, in which sialic acid is oxidized to formylpyruvic acid. This reacts with thiobarbituric acid to form a pink colored product. The colorimetric (549nm)/fluorimetric (λex = 555nm/λem = 585nm) product is directly proportional to sialic acid concentration in the sample.
General description: Sialic Acid is a general name for nine carbon acidic sugars with N- or O-substituted derivatives. The most common member of these sugars is N-acetylneuraminic acid (NANA). They are associated with carbohydrates and are localized on cell membranes. Sialic acid is widely distributed throughout mammalian tissues and fluids including serum. Sialylated oligosaccharides have been shown to exhibit antiviral properties and are also known to influence blood coagulation and cholesterol levels. The sialic acid level in body fluids is also an important marker for diagnosing cancer.
Storage Temp. −20°C
UNSPSC 12161503

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