SigmaMAb Antibody Drug Conjugate (ADC) Mimic
SIGMA/MSQC8 - Antibody Cysteine-Fluorophore Conjugate Standard
Synonym: Antibody Drug Conjugate
Product Type: Chemical
SigmaMAb Antibody-Drug Conjugate (ADC) Mimic, Cat. No. MSQC8: Non-toxic ADC-mimic, with Cys-conjugation to dansyl-cadaverine-SMCC.
| antibody product type | primary antibodies |
| form | lyophilized powder |
| Quality Level | 200  |
| recombinant | expressed in CHO cells |
| shipped in | wet ice |
| storage temp. | −20°C |
| Application: | Poster: Antibody Drug Conjugate Mimic Enables LC-MS Method Development Without Risk Poster: LC-UV-MS Method Development for Antibody Drug Conjugates Using a Non-Toxic ADC-Mimic Poster: LC-MS Method Development for Antibody Drug Conjugates Using a Non-Toxic ADC Mimic |
| General description: | SigmaMab Antibody Drug Conjugate (ADC) Mimic, is a non-toxic drug mimic that is utilized as a standard for mass spectrometry and high performance liquid chromatography. The ADC Mimic conjugates SigmaMab (MSQC4), an IgG1 monoclonal antibody, to dansyl fluorophores via an LC-SMCC crosslinker. This dansyl-LC-SMCC attachment serves as the substitution for the toxic payload of a real ADC. The ADC Mimic allows for safer and more consistent testing, making it the optimal product over real ADCs. It is also a more affordable product compared to real ADCs. With the help of this non-toxic product, LC-MS processes can be developed in a safer environment. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352204 |