N-Nitrosodiethylamine
SIGMA/N0258 - ISOPAC®
Synonym: Diethylnitrosamine
CAS Number: 55-18-5
Empirical Formula (Hill Notation): C4H10N2O
Molecular Weight: 102.14
EC Number: 200-226-1
MDL Number: MFCD00013890
Linear Formula: (C2H5)2NNO
Product Type: Chemical
| bp | 177 °C (lit.) |
| density | 0.95 g/mL (lit.) |
| form | liquid |
| InChI | 1S/C4H10N2O/c1-3-6(4-2)5- |
| InChI key | WBNQDOYYEUMPFS-UHFFFAOYSA |
| Quality Level | 100  |
| SMILES string | CCN(CC)N=O |
| Application: | N-Nitrosodiethylamine (NDEA) has been used as a hepatocarcinogen/DNA damaging agent. It has been used as a calibration standard for gas–liquid chromatography. |
| Biochem/physiol Actions: | N-Nitrosodiethylamine (NDEA) is a potent hepatocarcinogenic dialkylnitrosoamine. It is mainly present in tobacco smoke, water, cheddar cheese, cured, fried meals and many alcoholic beverages. NDEA is responsible for the changes in the nuclear enzymes associated with DNA repair/replication. It results in various tumors in all animal species. The main target organs are the nasal cavity, trachea, lung, esophagus and liver. |
| Disclaimer: | Injecting any compatible solvent permits preparation of any desired strength solution without exposure. |
| Legal Information: | Isopac is a registered trademark of Merck KGaA, Darmstadt, Germany |
| Packaging: | 1 g in serum bottle |
| Packaging: | Packaged in a 100 mL serum bottle with silicon/PTFE septum and aluminum tear seal. |
| Preparation Note: | Dissolving the contents in 100 mL of solvent yields a 1% solution. |
| Symbol |   GHS06,GHS08 |
| Signal word | Danger |
| Hazard statements | H301 - H350 - H412 |
| Precautionary statements | P202 - P264 - P270 - P273 - P280 - P301 + P310 |
| Hazard Codes | T |
| Risk Statements | 45-22 |
| Safety Statements | 53-45 |
| RIDADR | UN2810 - class 6.1 - PG 3 - RQ - Toxic, liquids, organic, n.o.s. |
| WGK Germany | WGK 3 |
| bp | 177 °C (lit.) |
| Density | 0.95 g/mL (lit.) |
| UNSPSC | 12352116 |