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(−)-Nicotine hemisulfate salt

SIGMA/N1019 - ≥95% (TLC), ~35 % (w/v) in H2O (based on free base)

Synonym: (−)-1-Methyl-2-(3-pyridyl)pyrrolidine

CAS Number: 65-30-5
Empirical Formula (Hill Notation): C20H28N4 · H2O4S
Molecular Weight: 422.54
MDL Number: MFCD00148918
Linear Formula: (C10H14N2)2 · H2SO4
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-N1019-25ML 25 mL
 $68.70
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45-N1019-100ML 100 mL
 $161.00
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This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: N1019-100ML.

 

assay ≥95% (TLC)
color dark brown
concentration ~35 % (w/v) in H2O (based on free base)
form liquid
InChI 1S/2C10H14N2.H2O4S/c2*1-12-7-3-5-10(12)9-4-2-6-11-8-9;1-5(2,3)4/h2*2,4,6,8,10H,3,5,7H2,1H3;(H2,1,2,3,4)/t2*10-;/m00./s1
InChI key IECQULMJVNSKDB-RCWTXCDDSA-N
Quality Level 100 
SMILES string OS(O)(=O)=O.CN1CCC[C@H]1c2cccnc2.CN3CCC[C@H]3c4cccnc4
Analysis Note: Mixture of nicotine base and nicotine sulfate.
Application: (−)-Nicotine hemisulfate salt has been used to study the influence of nicotine on the severity of choroidal neovascularization (CNV). It also has been used as a natural nectar alkaloid to study the effect of self-medication in bumblebees.
Biochem/physiol Actions: Prototype nicotinic acetylcholine receptor agonist; naturally occurring isomer.
Disclaimer: Shelf-life of the solution as supplied is at least six years when stored at room temperature.
General description: Nicotine is found in the leaves of Nicotiana species. It binds to nicotinic acetylcholine receptors and inhibits endogenous neurotransmitters. Nicotine is associated with lung cancer development and reduces the efficiency of chemotherapeutic agents. It is used to treat Alzheimer′s and Parkinson′s disease.
Packaging: 25, 100 mL in glass bottle
Purity ≥95% (TLC)
UNSPSC 12352210

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