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Nisoxetine hydrochloride

SIGMA/N151 - solid, ≥98% (HPLC)

Synonym: (±)-γ-(2-Methoxyphenoxy)-N-methyl-benzenepropanamine hydrochloride; LY-94,939

CAS Number: 57754-86-6
Empirical Formula (Hill Notation): C17H21NO2 · HCl
Molecular Weight: 307.82
MDL Number: MFCD00153850
Linear Formula: C17H21NO2 · HCl
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-N151-25MG 25 mg
 $416.00
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45-N151-100MG 100 mg
 $1250.00
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assay ≥98% (HPLC)
color white to beige
form solid
InChI 1S/C17H21NO2.ClH/c1-18-13-12-15(14-8-4-3-5-9-14)20-17-11-7-6-10-16(17)19-2;/h3-11,15,18H,12-13H2,1-2H3;1H
InChI key LCEURBZEQJZUPV-UHFFFAOYSA-N
Quality Level 100 
SMILES string Cl[H].CNCCC(Oc1ccccc1OC)c2ccccc2
solubility ethanol: 50 mg/mL
  H2O: 20 mg/mL
storage condition desiccated
Application: Nisoxetine has been used as a norepinephrine transport (NET) blocker in autoradiography studies. It has also been used as a NET blocker to study its effects on perivascular adipose tissue.
Biochem/physiol Actions: Nisoxetine is a selective and potent noradrenaline reuptake inhibitor. It has a high affinity towards the noradrenaline transporter. Nisoxetine possesses antidepressant activity.
Features and Benefits: This compound is featured on the Biogenic Amine Transporters  page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
Packaging: 25, 100 mg in glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
UNSPSC 12352200

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