Naltriben methanesulfonate hydrate
SIGMA/N156 - ≥98% (HPLC), solid
Synonym: NTB hydrate
CAS Number: 1309441-44-8
Empirical Formula (Hill Notation): C26H25NO4 · CH4O3S · xH2O
Molecular Weight: 511.59 (anhydrous basis)
MDL Number: MFCD11046015
Linear Formula: C26H25NO4 · CH4O3S · xH2O
Product Type: Chemical
| assay | ≥98% (HPLC) |
| color | off-white |
| drug control | regulated under CDSA - not available from Sigma-Aldrich Canada |
| form | solid |
| InChI | 1S/C26H25NO4.CH4O3S.H2O/c |
| InChI key | VAGWKZSGWSRENH-HIAJFTJMSA |
| Quality Level | 100  |
| SMILES string | O.CS(O)(=O)=O.Oc1ccc2C[C@ |
| solubility | DMSO: 14 mg/mL at ~60 °C |
| storage temp. | −20°C |
| Application: | Naltriben methanesulfonate hydrate has been used in the assessment of parasite growth and evaluation of growth inhibition. It has also been used to understand the action of deltorphin-II in exhibiting its antimalarial effect. |
| Biochem/physiol Actions: | Naltriben methanesulfonate is a highly selective δ2 opioid receptor antagonist. The relative ability of the delta antagonists benzylidenenaltrexone and naltriben to inhibit DPDPE-stimulated [35S]GTPgammaS binding suggests that the opioid receptor is of the delta-2 subtype. Ligand binding assays demonstrates biphasic binding of the antagonist to the single receptor type. [35S]GTPgammaS binding is also stimulated by [D-Ser2,Leu5,Thr6]enkepha |
| Packaging: | 5, 25, 100 mg in glass bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (HPLC) |
| Storage Temp. | −20°C |
| UNSPSC | 12352200 |