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NBQX disodium salt hydrate

SIGMA/N183 - ≥98% (HPLC)

Synonym: 1,2,3,4-Tetrahydro-6-nitro-2,3-dioxo-benzo[f]quinoxaline-7-sulfonamide disodium salt hydrate; FG 9202 disodium salt hydrate

CAS Number: 118876-58-7 (free acid)
Empirical Formula (Hill Notation): C12H6N4Na2O6S · xH2O
Molecular Weight: 380.24 (anhydrous basis)
MDL Number: MFCD12910445
Linear Formula: C12H6N4Na2O6S · xH2O
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-N183-5MG 5 mg
 $370.00
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45-N183-25MG 25 mg
 $1430.00
1/EA		 Add To Favorites

 

assay ≥98% (HPLC)
color , brown to dark red-brown
form lyophilized powder
InChI 1S/C12H8N4O6S.2Na.H2O/c13-23(21,22)8-3-1-2-5-9(8)7(16(19)20)4-6-10(5)15-12(18)11(17)14-6;;;/h1-4H,(H,14,17)(H,15,18)(H2,13,21,22);;;1H2/q;2*+1;/p-2
InChI key LQSCHRKYVVVUFA-UHFFFAOYSA-L
Quality Level 100 
SMILES string O.[Na+].[Na+].NS(=O)(=O)c1cccc2c1c(cc3nc([O-])c([O-])nc23)[N+]([O-])=O
solubility H2O: >10 mg/mL
storage condition desiccated
storage temp. 2-8°C
Application: NBQX disodium salt hydrate has been used:
• in N-methyl-D-aspartate receptor (NMDAR) kinetic studies
• as an α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor antagonist for the electrophysiological studies cultured neurons
• in the extracellular solution for current/voltage (I/V) relationship and rectification index experiments in excitatory postsynaptic currents (EPSCs) mediated by NMDA receptors (EPSCNMDAR)
Biochem/physiol Actions: NBQX disodium salt hydrate is a neuroprotective AMPA/kainate glutamate receptor antagonist.
Features and Benefits: This compound is a featured product for Neuroscience research. Click here  to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm .
Features and Benefits: This compound is featured on the Glutamate Receptors (Ion Channel Family)  page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
Packaging: 5, 25 mg in glass bottle
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

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