1-Naphthylacetyl spermine trihydrochloride

SIGMA/N193

Synonym: NASPM trihydrochloride

CAS Number: 1049731-36-3
Empirical Formula (Hill Notation): C₂₂H₃₄N₄O · 3HCl
Molecular Weight: 479.91
MDL Number: MFCD01321052
Linear Formula: C₂₂H₃₄N₄O · 3HCl
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-N193-5MG	5 mg	$214.00 1/EA		Add To Favorites
45-N193-25MG	25 mg	$731.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥95% (HPLC)
color	white
form	powder
InChI	1S/C22H34N4O.3ClH/c23-12-6-15-24-13-3-4-14-25-16-7-17-26-22(27)18-20-10-5-9-19-8-1-2-11-21(19)20;;;/h1-2,5,8-11,24-25H,3-4,6-7,12-18,23H2,(H,26,27);3*1H
InChI key	JNEOJAUJWOPWJS-UHFFFAOYSA-N
Quality Level	100
SMILES string	Cl.Cl.Cl.NCCCNCCCCNCCCNC(=O)Cc1cccc2ccccc12
solubility	H₂O: ≥20 mg/mL
storage condition	desiccated
	protect from light

Application:	1-Naphthylacetyl spermine trihydrochloride has been used for the inhibition of calcium-permeable AMPAR (α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor). It has also been used to study the involvement of AMPAR in biphasic activation of stress-activated protein kinase/extracellular signal-regulated kinase-1.
Biochem/physiol Actions:	Blocks Ca²⁺ permeable AMPA receptor channels.
Other Notes:	Synthetic analog of Joro spider toxin.
Packaging:	5, 25 mg in glass bottle

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥95% (HPLC)
UNSPSC	12352200

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