Naltrexone hydrochloride

SIGMA/N3136

Synonym: Naltrexone HCl

CAS Number: 16676-29-2
Empirical Formula (Hill Notation): C₂₀H₂₃NO₄ · HCl
Molecular Weight: 377.86
EC Number: 240-723-0
MDL Number: MFCD00069324
Linear Formula: C₂₀H₂₃NO₄ · HCl
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-N3136-100MG	100 mg	$108.00 1/EA		Add To Favorites
45-N3136-250MG	250 mg	$216.00 1/EA		Add To Favorites
45-N3136-1G	1 g	$651.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

form	powder
InChI	1S/C20H23NO4.ClH/c22-13-4-3-12-9-15-20(24)6-5-14(23)18-19(20,16(12)17(13)25-18)7-8-21(15)10-11-1-2-11;/h3-4,11,15,18,22,24H,1-2,5-10H2;1H/t15-,18+,19+,20-;/m1./s1
InChI key	RHBRMCOKKKZVRY-ITLPAZOVSA-N
originator	Novartis
Quality Level	100
SMILES string	Cl.Oc1ccc2C[C@H]3N(CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O)CC6CC6
storage temp.	2-8°C

Application:	Naltrexone hydrochloride has been used: • as an opioid antagonist, to analyse its effect on ethanol preference using Caenorhabditis elegans as a model • to determine its effectiveness in reducing the preference for substance of abuse (SOA) like nicotine and cocaine using Caenorhabditis elegans as a model • in the preparation of combinatorial drug, PXT3003 for treating Charcot-Marie-Tooth disease 1A (CMT1A) transgenic rat model Pmp22
Biochem/physiol Actions:	Competitive antagonist for μ, κ, δ, and σ-opioid receptors; has greater oral efficacy and longer duration of action than naloxone.
Features and Benefits:	This compound is featured on the Opioid Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
Features and Benefits:	This compound was developed by Novartis . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here .

Symbol	GHS07
Signal word	Warning
Hazard statements	H302
Precautionary statements	P264 - P270 - P301 + P312 - P501
Hazard Codes	Xn
Risk Statements	22
Safety Statements	22-36
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Storage Temp.	2-8°C
UNSPSC	12352200

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