(+)-Norfenfluramine hydrochloride

SIGMA/N3288 - ≥98% (HPLC), powder

Synonym: JP 92; NSC 43036; S-(+)-α-Methyl-3-(trifluoromethyl)benzeneethanamine hydrochloride

CAS Number: 37936-89-3
Empirical Formula (Hill Notation): C₁₀H₁₂F₃N · HCl
Molecular Weight: 239.67
MDL Number: MFCD11045299
Linear Formula: C₁₀H₁₂F₃N · HCl
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-N3288-10MG	10 mg	$186.00 1/EA	Add To Favorites
45-N3288-50MG	50 mg	$839.00 1/EA	Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥98% (HPLC)
color	white
drug control	regulated under CDSA - not available from Sigma-Aldrich Canada
form	powder
InChI	1S/C10H12F3N.ClH/c1-7(14)5-8-3-2-4-9(6-8)10(11,12)13;/h2-4,6-7H,5,14H2,1H3;1H/t7-;/m0./s1
InChI key	PIDLOFBRTWNFAR-FJXQXJEOSA-N
Quality Level	100
SMILES string	Cl.C[C@H](N)Cc1cccc(c1)C(F)(F)F
solubility	H₂O: >10 mg/mL
storage condition	desiccated
storage temp.	2-8°C

Biochem/physiol Actions:	(+)-Norfenfluramine is the major hepatic metabolite of (+)-fenfluramine and is primarily responsible for the anorexic effect, as well as side effects; (+)-norfenfluramine causes vasoconstriction and a blood pressure increase in rats with normal blood; acts primarily on the cytoplasmic pool of serotonin; more potent than fenfluramine at inducing dopamine release.
Biochem/physiol Actions:	Potent substrate for serotonin transporter; 5-HT_2A/2B agonist; anorectic
Packaging:	10, 50 mg in glass bottle

Symbol	GHS07
Signal word	Warning
Hazard statements	H315 - H319 - H335
Precautionary statements	P302 + P352 - P305 + P351 + P338
Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36/37
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98% (HPLC)
Storage Temp.	2-8°C
UNSPSC	12352116

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