Neurokinin B

SIGMA/N4143 - ≥95% (HPLC)

Synonym: β-Neurokinin; Neuromedin K

CAS Number: 86933-75-7
Empirical Formula (Hill Notation): C₅₅H₇₉N₁₃O₁₄S₂
Molecular Weight: 1210.42
MDL Number: MFCD00133665
Linear Formula: C₅₅H₇₉N₁₃O₁₄S₂
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-N4143-.5MG	0.5 mg	$209.00 1/EA		Add To Favorites
45-N4143-1MG	1 mg	$290.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥95% (HPLC)
form	powder
InChI	1S/C55H79N13O14S2/c1-30(2)21-38(50(77)62-36(47(57)74)17-19-83-5)61-43(69)28-59-55(82)46(31(3)4)68-54(81)40(23-33-15-11-8-12-16-33)65-51(78)39(22-32-13-9-7-10-14-32)64-53(80)42(26-45(72)73)67-52(79)41(24-34-27-58-29-60-34)66-49(76)37(18-20-84-6)63-48(75)35(56)25-44(70)71/h7-16,27,29-31,35-42,46H,17-26,28,56H2,1-6H3,(H2,57,74)(H,58,60)(H,59,82)(H,61,69)(H,62,77)(H,63,75)(H,64,80)(H,65,78)(H,66,76)(H,67,79)(H,68,81)(H,70,71)(H,72,73)
InChI key	NHXYSAFTNPANFK-UHFFFAOYSA-N
Quality Level	200
SMILES string	CSCCC(NC(=O)C(CC(C)C)NC(=O)CNC(=O)C(NC(=O)C(Cc1ccccc1)NC(=O)C(Cc2ccccc2)NC(=O)C(CC(O)=O)NC(=O)C(Cc3cnc[nH]3)NC(=O)C(CCSC)NC(=O)C(N)CC(O)=O)C(C)C)C(N)=O
storage temp.	−20°C
UniProt accession no.	Q9UHF0

Amino Acid Sequence:	Asp-Met-His-Asp-Phe-Phe-Val-Gly-Leu-Met-NH2
Biochem/physiol Actions:	Neurokinin B is a ten-residue peptide. It is an endogenous tachykinin agonist with preference for the NK-3 receptor. It is a potent bronchoconstrictor and may have a neuromodulatory role in the brain. Neurokinin B has a role in slow synaptic or non-synaptic communication.
Other Notes:	Lyophilized from 0.1% TFA in H2O

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥95% (HPLC)
Storage Temp.	−20°C
UNSPSC	51111800

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