Neurokinin A

SIGMA/N4267 - ≥97% (HPLC)

Synonym: α-Neurokinin; Neuromedin L; Substance K

CAS Number: 86933-74-6
Empirical Formula (Hill Notation): C₅₀H₈₀N₁₄O₁₄S
Molecular Weight: 1133.32
MDL Number: MFCD00167560
Linear Formula: C₅₀H₇₉N₁₃O₁₅S
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-N4267-.5MG	0.5 mg	$181.00 1/EA		Add To Favorites
45-N4267-1MG	1 mg	$245.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥97% (HPLC)
composition	Peptide content, ≥70%
form	powder
InChI	1S/C50H80N14O14S/c1-26(2)18-34(45(73)58-32(42(53)70)15-17-79-6)57-38(67)23-55-49(77)40(27(3)4)63-47(75)35(19-29-12-8-7-9-13-29)60-48(76)37(24-65)62-46(74)36(21-39(68)69)61-50(78)41(28(5)66)64-44(72)33(14-10-11-16-51)59-43(71)31(52)20-30-22-54-25-56-30/h7-9,12-13,22,25-28,31-37,40-41,65-66H,10-11,14-21,23-24,51-52H2,1-6H3,(H2,53,70)(H,54,56)(H,55,77)(H,57,67)(H,58,73)(H,59,71)(H,60,76)(H,61,78)(H,62,74)(H,63,75)(H,64,72)(H,68,69)
InChI key	HEAUFJZALFKPBA-UHFFFAOYSA-N
Quality Level	200
SMILES string	CSCCC(NC(=O)C(CC(C)C)NC(=O)CNC(=O)C(NC(=O)C(Cc1ccccc1)NC(=O)C(CO)NC(=O)C(CC(O)=O)NC(=O)C(NC(=O)C(CCCCN)NC(=O)C(N)Cc2cnc[nH]2)C(C)O)C(C)C)C(N)=O
storage temp.	−20°C
UniProt accession no.	P20366

Amino Acid Sequence:	His-Lys-Thr-Asp-Ser-Phe-Val-Gly-Leu-Met-NH2
Biochem/physiol Actions:	Neurokinin A improves the multiplication and paracrine ability of stem cells acquired from adipose in vitro. It participates in the movement of several organ tracts, triggers glandular secretion and controls autonomic reflexes. Neurokinin A plays an important role in neuroimmune and systemic autoimmune/inflammatory conditions like multiple sclerosis (MS), rheumatoid arthritis, inflammatory bowel disease and also in infections and cancer.
General description:	Neurokinin A is an 11 amino acid peptide. It is a member of tachykinin family, which includes neurokinin A, neurokinin B, neuropeptide K, neuropeptide Y and hemokinin-1. The gene encoding neurokinin A is localized on human chromosome 7q21.3.
Other Notes:	Lyophilized from 0.1% TFA in H2O

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥97% (HPLC)
Storage Temp.	−20°C
UNSPSC	51111800

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