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Nalidixic acid sodium salt

SIGMA/N4382 - powder

Synonym: 1-Ethyl-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid sodium salt

CAS Number: 3374-05-8
Empirical Formula (Hill Notation): C12H11N2NaO3
Molecular Weight: 254.22
EC Number: 222-159-7
MDL Number: MFCD00064376
Linear Formula: C12H11N2NaO3
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-N4382-1G 1 g
 $29.80
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45-N4382-5G 5 g
 $81.70
1/EA		 Add To Favorites
45-N4382-25G 25 g
 $281.00
1/EA		 Add To Favorites
45-N4382-100G 100 g
 $881.00
1/EA		 Add To Favorites

 

antibiotic activity spectrum Gram-negative bacteria
  Gram-positive bacteria
form powder
InChI 1S/C12H12N2O3.Na/c1-3-14-6-9(12(16)17)10(15)8-5-4-7(2)13-11(8)14;/h4-6H,3H2,1-2H3,(H,16,17);/q;+1/p-1
InChI key ROKRAUFZFDQWLE-UHFFFAOYSA-M
mode of action DNA synthesis | interferes
  enzyme | inhibits
originator Sanofi Aventis
Quality Level 200 
SMILES string [Na+].CCN1C=C(C([O-])=O)C(=O)c2ccc(C)nc12
Application: Nalidixicacid has been used to treat the bacterial cultures to study itsresistance on Salmonella enterica and SalmonellaTyphimurium.
Biochem/physiol Actions: Nalidixic acid sodium salt is an inhibitor of bacterial DNA polymerase (DNA gyrase) and avian myeloblastoma virus reverse transcriptase. Inhibits nucleic acid and protein synthesis in Saccharomyces cerevisiae.
Features and Benefits: This compound is a featured product for Apoptosis research. Click here  to discover more featured Apoptosis products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm .
Features and Benefits: This compound was developed by Sanofi Aventis . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here .
General description: Chemical structure: quinolone
General description: Nalidixic acid is a quinolone and can block the activity of bacterial topoisomerase type II enzyme, thereby stopping bacterial replication. It is a potential antibacterial agent against Gram-negative bacteria than Gram-positive bacteria. Nalidixic acid has been studied in the management of urinary tract infections.
Packaging: 1, 5, 25, 100 g in glass bottle
UNSPSC 12352106

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