N_ω-Nitro-L-arginine

SIGMA/N5501 - ≥98% (TLC)

Synonym: L-NNA; N⁵-(Nitroamidino)-L-2,5-diaminopentanoic acid; N^G-NO₂-L-Arg

CAS Number: 2149-70-4
Empirical Formula (Hill Notation): C₆H₁₃N₅O₄
Molecular Weight: 219.20
EC Number: 218-418-9
MDL Number: MFCD00007033
Linear Formula: C₆H₁₃N₅O₄
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-N5501-1G	1 g	$29.80 1/EA	Add To Favorites
45-N5501-5G	5 g	$73.00 1/EA	Add To Favorites
45-N5501-25G	25 g	$283.00 1/EA	Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥98% (TLC)
biological source	synthetic
form	powder
InChI	1S/C6H13N5O4/c7-4(5(12)13)2-1-3-9-6(8)10-11(14)15/h4H,1-3,7H2,(H,12,13)(H3,8,9,10)/t4-/m0/s1
InChI key	MRAUNPAHJZDYCK-BYPYZUCNSA-N
mp	257 °C
Quality Level	200
SMILES string	N[C@@H](CCCNC(=N)N[N+]([O-])=O)C(O)=O
solubility	1 M HCl: 50 mg/mL, clear, colorless to faintly yellow

Application:	N_ω-Nitro-L-arginine has been used: • as nitric oxide synthase (NOS) inhibitor, to measure the release of nitric oxide (NO) derivatives in cytochrome c reduction assay • to pretreat fiber bundles for contractile studies • as NOS inhibitor to characterize the generation of NO in Taxus yunnanensis cells • as an irreversible inhibitor of the neuronal NO synthase (nNOS) to preincubate swimbladder preparations
Biochem/physiol Actions:	Irreversible inhibitor of constitutive nitric oxide synthase (nNOS) and a reversible inhibitor of inducible nitric oxide synthase (iNOS).
Biochem/physiol Actions:	N_ω-Nitro-L-arginine/L-NNA helps to reduce the levels of cortical hyperemia and brain cGMP occurring due to hypercapnia.
Features and Benefits:	This compound is featured on the Nitric Oxide Synthases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
Packaging:	1 g in poly tube
Packaging:	5, 25 g in poly bottle

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98% (TLC)
mp	257 °C
UNSPSC	12352209

To Order From a Quote