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Nicotinic acid adenine dinucleotide phosphate sodium salt

SIGMA/N5655 - ≥92.5%

Synonym: β-NAADP

CAS Number: 5502-96-5
Empirical Formula (Hill Notation): C21H27N6O18P3 · xNa+
Molecular Weight: 744.39 (free acid basis)
MDL Number: MFCD00274064
Linear Formula: C21H27N6O18P3 · xNa+
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-N5655-10MG 10 mg
 $512.00
1/EA		 Add To Favorites
45-N5655-25MG 25 mg
 $1070.00
1/EA		 Add To Favorites
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: N5655-25MG

 

assay ≥92.5%
form solid
InChI 1S/C21H27N6O18P3.Na/c22-17-12-18(24-7-23-17)27(8-25-12)20-16(44-46(33,34)35)14(29)11(43-20)6-41-48(38,39)45-47(36,37)40-5-10-13(28)15(30)19(42-10)26-3-1-2-9(4-26)21(31)32;/h1-4,7-8,10-11,13-16,19-20,28-30H,5-6H2,(H6-,22,23,24,31,32,33,34,35,36,37,38,39);/q;+1/p-1/t10?,11-,13+,14-,15+,16-,19+,20-;/m1./s1
InChI key KKCRODBDXQTAPI-NZNNTXIPSA-M
Quality Level 200 
SMILES string [Na+].Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP([O-])(=O)OP([O-])(=O)OCC4O[C@@H]([C@@H](O)[C@H]4O)[n+]5cccc(c5)C(O)=O)[C@@H](O)[C@H]3OP(O)(O)=O
storage temp. −20°C
Application: Nicotinic acid adenine dinucleotide phosphate sodium salt has been used for agonist injection into unfertilized eggs and embryos.
Biochem/physiol Actions: Potent activator of intracellular Ca2+ release via an IP3 and cyclic ADP ribose-independent mechanism.
General description: NAADP induces Ca2+ release from the eggs of sea urchin, when injected into the cell. It can be enzymatically produced from nicotinamide adenine dinucleotide phosphate (β-NADP) with the help of ADP-ribosyl cyclase.
Other Notes: Note: Should not be confused with nicotinamide adenine dinucleotide phosphate (NADP).
Packaging: 10, 25 mg in poly bottle
Preparation Note: Enzymatically prepared analog of β-NADP+.
Purity ≥92.5%
Storage Temp. −20°C
UNSPSC 12352106

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