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β-Nicotinamide adenine dinucleotide phosphate hydrate

SIGMA/N5755

Synonym: β-NADP; Coenzyme II; NADP; TPN; Triphosphopyridine nucleotide

CAS Number: 53-59-8 (anhydrous)
Empirical Formula (Hill Notation): C21H28N7O17P3 · xH2O
Molecular Weight: 743.41 (anhydrous basis)
MDL Number: MFCD10567218
Linear Formula: C21H28N7O17P3 · xH2O
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-N5755-100MG 100 mg
 $182.00
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45-N5755-250MG 250 mg
 $319.00
1/EA		 Add To Favorites
45-N5755-500MG 500 mg
 $585.00
1/EA		 Add To Favorites
45-N5755-1G 1 g
 $955.00
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This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: N5755-100MG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: N5755-250MG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: N5755-500MG

 

assay ≥95% (HPLC)
  ≥95% (spectrophotometric assay)
biological source chicken liver
cation traces sodium and potassium: ≤0.04%
form powder
InChI 1S/C21H28N7O17P3.H2O/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(44-46(33,34)35)14(30)11(43-21)6-41-48(38,39)45-47(36,37)40-5-10-13(29)15(31)20(42-10)27-3-1-2-9(4-27)18(23)32;/h1-4,7-8,10-11,13-16,20-21,29-31H,5-6H2,(H7-,22,23,24,25,32,33,34,35,36,37,38,39);1H2/t10-,11-,13-,14-,15-,16-,20-,21-;/m1./s1
InChI key ZKJOXOJMGXFSPF-QYZPTAICSA-N
Quality Level 200 
SMILES string O.NC(=O)c1ccc[n+](c1)[C@@H]2O[C@H](COP([O-])(=O)OP(O)(=O)OC[C@H]3O[C@H]([C@H](OP(O)(O)=O)[C@@H]3O)n4cnc5c(N)ncnc45)[C@@H](O)[C@H]2O
solubility H2O: soluble 50 mg/mL, clear, colorless to faintly yellow
storage temp. −20°C
Application: β-Nicotinamide adenine dinucleotide phosphate hydrate is suitable for use in:
• the measurement of Glucose-6-phosphate dehydrogenase activity
• the Cytochrome P450 3A4 assay as a part of NADPH-regenerating system
• the Cytochrome P450 2D6 assay as a part of NADPH-regenerating system
• the determination of Glucose-6-phosphate content
Biochem/physiol Actions: Electron acceptor
Biochem/physiol Actions: β-Nicotinamide adenine dinucleotide 2′-phosphate (NADP+) and β-Nicotinamide adenine dinucleotide 2′-phosphate, reduced (NADPH) comprise a coenzyme redox pair (NADP+:NADPH) involved in a wide range of enzyme catalyzed oxidation reduction reactions. The NADP+/NADPH redox pair facilitates electron transfer in anabolic reactions such as lipid and cholesterol biosynthesis and fatty acyl chain elongation. The NADP+/NADPH redox pair is used in a variety of antioxidation mechanism where it protects agains reactive oxidation species accumulation. NADPH is generated in vivio by the pentose phosphate pathway (PPP).
Other Notes: Packaged based on solid weight.
Other Notes: This is a common form of NADP.
Packaging: 1 g in glass bottle
Packaging: 100, 250, 500 mg in glass bottle
Purity ≥95% (HPLC); ≥95% (spectrophotometric assay)
Storage Temp. −20°C
UNSPSC 41106305

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