β-Nicotinamide adenine dinucleotide 2′-phosphate reduced tetrasodium salt hydrate
SIGMA/N6505 - ≥95% (HPLC)
Synonym: β-NADPH; 2′-NADPH hydrate; Coenzyme II reduced tetrasodium salt; Dihydronicotinamide adenine dinucleotide phosphate tetrasodium salt; NADPH Na4; TPNH2 Na4; Triphosphopyridine nucleotide reduced tetrasodium salt
CAS Number: 2646-71-1 (anhydrous)
Empirical Formula (Hill Notation): C21H26N7Na4O17P3 · xH2O
Molecular Weight: 833.35 (anhydrous basis)
MDL Number: MFCD00036263
Linear Formula: C21H26N7Na4O17P3 · xH2O
Product Type: Chemical
| assay | ≥95% (HPLC) |
| ≥95% (spectrophotometric assay) | |
| biological source | chicken liver |
| form | powder |
| InChI | 1S/C21H30N7O17P3.4Na/c22- |
| InChI key | WYWWVJHQDVCHKF-MPUNMZHWSA |
| Quality Level | 200 ![]() |
| SMILES string | [Na+].[Na+].[Na+].[Na+].N |
| solubility | 10 mM NaOH: soluble-50 mg/mL, clear, faintly to light yellow |
| storage temp. | −20°C |
| Application: | β-Nicotinamide adenine dinucleotide 2′-phosphate (NADP+) and β-Nicotinamide adenine dinucleotide 2′-phosphate, reduced (NADPH) comprise a coenzyme redox pair (NADP+:NADPH) involved in a wide range of enzyme catalyzed oxidation reduction reactions. The NADP+/NADPH redox pair facilitates electron transfer in anabolic reactions such as lipid and cholesterol biosynthesis and fatty acyl chain elongation. The NADP+/NADPH redox pair is used in a variety of antioxidation mechanism where it protects agains reactive oxidation species accumulation. NADPH is generated in vivio by the pentose phosphate pathway (PPP). |
| Biochem/physiol Actions: | NADPH is an electron donor and a cofactor for many redox enzymes including nitric oxide synthetase. |
| Other Notes: | Packaged based on solid weight. |
| Packaging: | 1 g in poly bottle |
| Packaging: | 25, 100, 250, 500 mg in poly bottle |
| Preparation Note: | Enzymatically reduced. |
| Hazard Codes | F |
| Risk Statements | 11 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥95% (HPLC); ≥95% (spectrophotometric assay) |
| Storage Temp. | −20°C |
| UNSPSC | 41106305 |

