α-Nicotinamide adenine dinucleotide

SIGMA/N6754 - from Saccharomyces cerevisiae, ≤1% β-isomer, ≥95%

Synonym: α-DPN; α-Diphosphopyridine nucleotide; α-NAD

CAS Number: 7298-93-3
Empirical Formula (Hill Notation): C₂₁H₂₇N₇O₁₄P₂
Molecular Weight: 663.43
EC Number: 230-738-0
MDL Number: MFCD00134828
Linear Formula: C₂₁H₂₇N₇O₁₄P₂
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-N6754-10MG	10 mg	$125.00 1/EA	Add To Favorites
45-N6754-25MG	25 mg	$213.00 1/EA	Add To Favorites
45-N6754-100MG	100 mg	$656.00 1/EA	Add To Favorites
45-N6754-250MG	250 mg	$1390.00 1/EA	Add To Favorites

This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: N6754-100MG

Properties
Descriptions
Safety Info.
Basic Data

assay	≥95%
biological source	Saccharomyces cerevisiae
form	powder
impurities	≤1% β-isomer
InChI	1S/C21H27N7O14P2/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(32)14(30)11(41-21)6-39-44(36,37)42-43(34,35)38-5-10-13(29)15(31)20(40-10)27-3-1-2-9(4-27)18(23)33/h1-4,7-8,10-11,13-16,20-21,29-32H,5-6H2,(H5-,22,23,24,25,33,34,35,36,37)/t10-,11-,13-,14-,15-,16-,20+,21-/m1/s1
InChI key	BAWFJGJZGIEFAR-OPDHFMQKSA-N
Quality Level	200
SMILES string	NC(=O)c1ccc[n+](c1)[C@H]2O[C@H](COP([O-])(=O)OP(O)(=O)OC[C@H]3O[C@H]([C@H](O)[C@@H]3O)n4cnc5c(N)ncnc45)[C@@H](O)[C@H]2O
solubility	H₂O: soluble-50 mg/mL, clear, colorless to faintly yellow
storage temp.	−20°C

Application:	α-Nicotinamide adenine dinucleotide (αNAD) may be used together with other NAD analogues to study the specificity and kinetics of NAD-dependent and NAD-transporting enzymes and proteins, such as NAD-glycohydrolase(s) and the mitochondrial NAD+ transporter in Saccharomyces cerevisiae.
Application:	α-Nicotinamide adenine dinucleotide has been used in superoxide dismutase activity of seminal plasma samples and in glutathione peroxidase assay of liver, kidney, testes and brain samples.
Biochem/physiol Actions:	α-Nicotinamide adenine dinucleotide (α-NAD) is a substrate for renalase. α-NAD, an analog of β-NAD, when used modulates kinetics of NAD dependent enzymes.
Disclaimer:	This is not the common NAD required in the usual enzyme systems.
General description:	Nicotinamide adenine dinucleotide (NAD) is an important cofactor for oxidation-reduction reactions in mitochondria.
Other Notes:	α analog of β-NAD
Packaging:	10, 25, 100, 250 mg in poly bottle

Symbol	GHS07
Signal word	Warning
Hazard statements	H315 - H319 - H335
Precautionary statements	P302 + P352 - P305 + P351 + P338
Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	22-26-36
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3

Purity	≥95%
Storage Temp.	−20°C
UNSPSC	41106305

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