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DL-Norvaline

SIGMA/N7502

Synonym: (±)-2-Aminopentanoic acid

CAS Number: 760-78-1
Empirical Formula (Hill Notation): C5H11NO2
Molecular Weight: 117.15
EC Number: 212-082-7
MDL Number: MFCD00064420
Linear Formula: CH3CH2CH2CH(NH2)COOH
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-N7502-25G 25 g
 $65.40
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This image depicts SKU: N7502-25G

 

assay ≥98% (HPLC)
color white
form powder
InChI 1S/C5H11NO2/c1-2-3-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)
InChI key SNDPXSYFESPGGJ-UHFFFAOYSA-N
mp >300 °C
Quality Level 200 
SMILES string CCCC(N)C(O)=O
technique(s) HPLC: suitable
Application: DL-Norvaline has been used as an internal standard:
• to analyze metabolites in cultured mammalian cells by gas chromatography-mass spectrometry (GC-MS)
• to convert cysteine and cystine to Cys MPA (S-2-carboxyethylthio-L-cysteine) and quantify the same using a high-performance liquid chromatography (HPLC) analyzer
• for free amino acid analysis in samples of oocytes by liquid chromatography
Biochem/physiol Actions: DL-Norvaline is a neurotransmitter.
Biochem/physiol Actions: Norvaline mediates physiological and pathophysiological processes promoting nitric oxide production. It is used to treat Alzheimer′s disease and is effective against artificial metabolic syndrome in rats. Norvaline exhibits phase transition upon cooling below 190 K and hence it is useful in molecular machines. DL-Norvaline serves as a prototype for research in polymorphism and molecular dynamics of aliphatic α-amino acids containing linear side-chain. It influences the activity, stability, and side-chain packaging of proteins.
General description: Norvaline is a non-proteinogenic α-amino acid and is also called DL-α-aminovaleric acid. It is produced in Gram-negative microorganisms including Escherichia coli and is also a part of the antifungal peptide produced by Bacillus subtilis.
Packaging: 25, 100 g in poly bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
mp >300 °C
UNSPSC 12352209

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