4-Nitrophenyl acetate
SIGMA/N8130 - esterase substrate
Synonym: Acetic acid 4-nitrophenyl ester
CAS Number: 830-03-5
Empirical Formula (Hill Notation): C8H7NO4
Molecular Weight: 181.15
EC Number: 212-593-5
MDL Number: MFCD00007326
Linear Formula: CH3CO2C6H4NO2
Product Type: Chemical
| assay | ≥98% (TLC) |
| form | powder or crystals |
| InChI | 1S/C8H7NO4/c1-6(10)13-8-4 |
| InChI key | QAUUDNIGJSLPSX-UHFFFAOYSA |
| mp | 75-77 °C (lit.) |
| Quality Level | 200 ![]() |
| SMILES string | CC(=O)Oc1ccc(cc1)[N+]([O- |
| storage temp. | −20°C |
| Application: | 4-Nitrophenyl acetate has been used: • to evaluate esterase activity in human embryonic kidney cell line • in carbonic anhydrase inhibition assay • to study its conversion to p-nitrophenol (p-NP) by the esterase activity of bovine serum albumin • as a substrate to determine carboxylesterase (CES) activity in mouse liver cells • to study the advantages of bioconjugation of cross-linked enzyme aggregates (CLEAs) and magnetic iron oxide nanoparticles (MIONPs) in magnetic CLEAs matrix |
| General description: | Chromogenic esterase substrate. |
| Packaging: | 5, 10, 25, 100 g in poly bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (TLC) |
| mp | 75-77 °C (lit.) |
| Storage Temp. | −20°C |
| UNSPSC | 12352204 |

