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β-Nicotinamide adenine dinucleotide

SIGMA/N8410 - pkg of 20 mg (per vial)

Synonym: β-DPN; β-NAD; Coenzyme 1; Cozymase; DPN; Diphosphopyridine nucleotide; Nadide

CAS Number: 53-84-9
Empirical Formula (Hill Notation): C21H27N7O14P2
Molecular Weight: 663.43
EC Number: 200-184-4
MDL Number: MFCD00036253
Linear Formula: C21H27N7O14P2
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-N8410-15VL 15 vials
 $807.00
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form powder
InChI 1S/C21H27N7O14P2/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(32)14(30)11(41-21)6-39-44(36,37)42-43(34,35)38-5-10-13(29)15(31)20(40-10)27-3-1-2-9(4-27)18(23)33/h1-4,7-8,10-11,13-16,20-21,29-32H,5-6H2,(H5-,22,23,24,25,33,34,35,36,37)/t10-,11-,13-,14-,15-,16-,20-,21-/m1/s1
InChI key BAWFJGJZGIEFAR-NNYOXOHSSA-N
packaging pkg of 20 mg (per vial)
Quality Level 200 
SMILES string NC(=O)c1ccc[n+](c1)[C@@H]2O[C@H](COP([O-])(=O)OP(O)(=O)OC[C@H]3O[C@H]([C@H](O)[C@@H]3O)n4cnc5c(N)ncnc45)[C@@H](O)[C@H]2O
storage temp. −20°C
Application: β-Nicotinamide adenine dinucleotide (NAD+) and β-Nicotinamide adenine dinucleotide, reduced (NADH) comprise a coenzyme redox pair (NAD+:NADH) involved in a wide range of enzyme catalyzed oxidation reduction reactions. In addition to its redox function, NAD+/NADH is a donor of ADP-ribose units in ADP-ribosylaton (ADP-ribosyltransferases; poly(ADP-ribose) polymerases ) reactions and a precursor of cyclic ADP-ribose (ADP-ribosyl cyclases).
Application: β-Nicotinamide adenine dinucleotide has been used in the master mix for coupled enzyme assay to estimate pectin methylesterase activity.
Biochem/physiol Actions: Electron acceptor
Biochem/physiol Actions: β-Nicotinamide adenine dinucleotide (β-NADH) reduced form is an essential cofactor in all the living organisms. β-NADH functions as a hydride acceptors in biochemical redox reactions. It acts as a cell signaling molecule and is a potent neurotransmitter and neuromodulator in the peripheral nervous system. In brain, it mediates Ca2+ homeostasis, energy metabolism, aging and neuronal death.
Other Notes: Packaged based on NAD content as determined by UV-Vis.
Other Notes: This is the common form of NAD.
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Storage Temp. −20°C
UNSPSC 41106305

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