Nilutamide

SIGMA/N8534 - solid

Synonym: 5,5-Dimethyl-3-[4-nitro-3-(trifluoromethyl)phenyl]-2,4-imidazolidinedione; Anandron; RU-23908

CAS Number: 63612-50-0
Empirical Formula (Hill Notation): C₁₂H₁₀F₃N₃O₄
Molecular Weight: 317.22
MDL Number: MFCD00864670
Linear Formula: C₁₂H₁₀F₃N₃O₄
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-N8534-1G	1 g	$117.00 1/EA	Add To Favorites

This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: N8534-1G

Properties
Descriptions
Safety Info.
Basic Data

form	solid
InChI	1S/C12H10F3N3O4/c1-11(2)9(19)17(10(20)16-11)6-3-4-8(18(21)22)7(5-6)12(13,14)15/h3-5H,1-2H3,(H,16,20)
InChI key	XWXYUMMDTVBTOU-UHFFFAOYSA-N
originator	Sanofi Aventis
Quality Level	200
SMILES string	CC1(C)NC(=O)N(c2ccc(c(c2)C(F)(F)F)[N+]([O-])=O)C1=O

Application:	Nilutamide has been used: • as a nuclear androgen receptor (nAR) inhibitor to study its effects on oocyte maturation in zebrafish • to determine its effects on bioluminescent Saccharomyces cerevisiae bioreporters in BLYAS assay • as a substrate in hydrogenation reaction
Biochem/physiol Actions:	Nilutamide is a nuclear androgen receptor inhibitor. It is a nonsteroidal antiandrogen that competitively inhibits the binding of dihydrotestosterone to the androgen receptor. Nilutamide shows a therapeutic effect against prostate cancer.
Features and Benefits:	This compound is featured on the Nuclear Receptors (Steroids) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
Features and Benefits:	This compound was developed by Sanofi Aventis . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here .
Packaging:	1 g in glass bottle

Symbol	GHS06,GHS08
Signal word	Danger
Hazard statements	H301 - H360
Precautionary statements	P201 - P301 + P310 + P330
Hazard Codes	T
Risk Statements	60-25
Safety Statements	36/37/39-45
RIDADR	UN 2811 6.1 / PGIII
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

UNSPSC

51111800

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