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NF 023 hydrate

SIGMA/N8652 - ≥98% (HPLC), solid

Synonym: 8,8′-[Carbonylbis(imino-3,1-phenylene carbonylimino)]bis(1,3,5-naphthalene-trisulfonic acid) hexasodium salt hydrate

CAS Number: 104869-31-0 (anhydrous)
Empirical Formula (Hill Notation): C35H20N4O21S6 · 6Na · xH2O
Molecular Weight: 1162.88 (anhydrous basis)
MDL Number: MFCD11046019
Linear Formula: C35H20N4O21S6 · 6Na · xH2O
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-N8652-10MG 10 mg
 $205.00
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45-N8652-50MG 50 mg
 $663.00
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This picture is provided solely for illustration purposes, it may have been created or edited with AI. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.
This image depicts N8652-50MG.

 

assay ≥98% (HPLC)
color white to off-white
form solid
InChI 1S/C35H26N4O21S6.6Na.H2O/c40-33(38-25-7-9-27(63(49,50)51)23-13-21(61(43,44)45)15-29(31(23)25)65(55,56)57)17-3-1-5-19(11-17)36-35(42)37-20-6-2-4-18(12-20)34(41)39-26-8-10-28(64(52,53)54)24-14-22(62(46,47)48)16-30(32(24)26)66(58,59)60;;;;;;;/h1-16H,(H,38,40)(H,39,41)(H2,36,37,42)(H,43,44,45)(H,46,47,48)(H,49,50,51)(H,52,53,54)(H,55,56,57)(H,58,59,60);;;;;;;1H2/q;6*+1;/p-6
InChI key FLINBQMOKZJBEC-UHFFFAOYSA-H
Quality Level 100 
SMILES string O.[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[O-]S(=O)(=O)c1cc(c2c(NC(=O)c3cccc(NC(=O)Nc4cccc(c4)C(=O)Nc5ccc(c6cc(cc(c56)S([O-])(=O)=O)S([O-])(=O)=O)S([O-])(=O)=O)c3)ccc(c2c1)S([O-])(=O)=O)S([O-])(=O)=O
solubility H2O: >20 mg/mL
storage condition desiccated
Application: NF 023 hydrate has been used as an inhibitor of methyltransferases. It has also been used to test its inhibitory effect on human adenovirus type-37 (HAdV-D37) viral infection in human corneal epithelial (HCE) cells.
Biochem/physiol Actions: NF 023 contains six benzene rings and is a suramin analog. It is a potent, competitive, and selective P2X purinoceptor antagonist that aids in discriminating between P2X receptor subtypes.
Features and Benefits: This compound is featured on the P2 Receptors: P2X Ion Channel Family  page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
Packaging: 10, 50 mg in glass bottle
Packaging: Desiccate
Purity ≥98% (HPLC)
UNSPSC 12352200

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