Synonym: 8,8′-[Carbonylbis(imino-3,1-phenylene carbonylimino)]bis(1,3,5-naphthalene-trisulfonic acid) hexasodium salt hydrate
CAS Number: 104869-31-0 (anhydrous)
Empirical Formula (Hill Notation): C35H20N4O21S6 · 6Na · xH2O
Molecular Weight: 1162.88 (anhydrous basis)
MDL Number: MFCD11046019
Linear Formula: C35H20N4O21S6 · 6Na · xH2O
Product Type: Chemical
| assay |
≥98% (HPLC) |
| color |
white to off-white |
| form |
solid |
| InChI |
1S/C35H26N4O21S6.6Na.H2O/c40-33(38-25-7-9-27(63(49,50)51)23-13-21(61(43,44)45)15-29(31(23)25)65(55,56)57)17-3-1-5-19(11-17)36-35(42)37-20-6-2-4-18(12-20)34(41)39-26-8-10-28(64(52,53)54)24-14-22(62(46,47)48)16-30(32(24)26)66(58,59)60;;;;;;;/h1-16H,(H,38,40)(H,39,41)(H2,36,37,42)(H,43,44,45)(H,46,47,48)(H,49,50,51)(H,52,53,54)(H,55,56,57)(H,58,59,60);;;;;;;1H2/q;6*+1;/p-6 |
| InChI key |
FLINBQMOKZJBEC-UHFFFAOYSA-H |
| Quality Level |
100  |
| SMILES string |
O.[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[O-]S(=O)(=O)c1cc(c2c(NC(=O)c3cccc(NC(=O)Nc4cccc(c4)C(=O)Nc5ccc(c6cc(cc(c56)S([O-])(=O)=O)S([O-])(=O)=O)S([O-])(=O)=O)c3)ccc(c2c1)S([O-])(=O)=O)S([O-])(=O)=O |
| solubility |
H2O: >20 mg/mL |
| storage condition |
desiccated |
| Application: |
NF 023 hydrate has been used as an inhibitor of methyltransferases. It has also been used to test its inhibitory effect on human adenovirus type-37 (HAdV-D37) viral infection in human corneal epithelial (HCE) cells. |
| Biochem/physiol Actions: |
NF 023 contains six benzene rings and is a suramin analog. It is a potent, competitive, and selective P2X purinoceptor antagonist that aids in discriminating between P2X receptor subtypes. |
| Features and Benefits: |
This compound is featured on the P2 Receptors: P2X Ion Channel Family page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here . |
| Packaging: |
10, 50 mg in glass bottle |
| Packaging: |
Desiccate |
| Purity |
≥98% (HPLC) |
| UNSPSC |
12352200 |
GHS07