Olopatadine hydrochloride

SIGMA/O0391 - ≥98% (HPLC)

Synonym: (11Z)-11-[3-(Dimethylamino)propylidene]-6,11-dihydrodibenz[b,e]oxepin-2-acetic acid hydrochloride; AL-4943A; KW-4679; Opatanol; Patanol

CAS Number: 140462-76-6
Empirical Formula (Hill Notation): C₂₁H₂₃NO₃·HCl
Molecular Weight: 373.87
MDL Number: MFCD00875716
Linear Formula: C₂₁H₂₃NO₃·HCl
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-O0391-10MG	10 mg	$94.80 1/EA	Add To Favorites
45-O0391-50MG	50 mg	$376.00 1/EA	Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥98% (HPLC)
form	solid
InChI	1S/C21H23NO3.ClH/c1-22(2)11-5-8-18-17-7-4-3-6-16(17)14-25-20-10-9-15(12-19(18)20)13-21(23)24;/h3-4,6-10,12H,5,11,13-14H2,1-2H3,(H,23,24);1H/b18-8-;
InChI key	HVRLZEKDTUEKQH-NOILCQHBSA-N
Quality Level	100
SMILES string	Cl.CN(C)CCC=C1c2ccccc2COc3ccc(CC(O)=O)cc13
solubility	H₂O: ≥20 mg/mL
storage temp.	room temp

Biochem/physiol Actions:	Olopatadine is a dual acting histamine H1-receptor antagonist and mast cell stabilizer.
Biochem/physiol Actions:	Olopatadine is a histamine H1 receptor antagonist and mast cell stabilizer. The low level of occupancy H1 receptors in the brain explains the low sedation effect of olopatidine. It is believed that olopatidine is a substrate for P-glycoprotein, which limits its brain penetration.
Packaging:	10, 50 mg in glass bottle

Symbol	GHS06,GHS09
Signal word	Danger
Hazard statements	H301 - H400
Precautionary statements	P273 - P301 + P310 + P330
Hazard Codes	T,N
Risk Statements	25-50
Safety Statements	45-61
RIDADR	UN 2811 6.1 / PGIII
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98% (HPLC)
Storage Temp.	room temp
UNSPSC	12352200

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