Ovalbumin (323-339) (chicken, Japanese quail)
SIGMA/O1641
Product Type: Chemical
| assay | 97-100% (HPLC) |
| color | white |
| composition | peptide content, 65-100% |
| form | lyophilized powder |
| Quality Level | 200  |
| solubility | water, double-distilled: soluble |
| storage temp. | −20°C |
| Amino Acid Sequence: | H-Ile-Ser-Gln-Ala-Val-His |
| Application: | Ovalbumin (323-339) (chicken, Japanese quail) has been used to induce allergic asthma in mice. |
| Biochem/physiol Actions: | Ovalbumin (OVA) peptide 323-339 mediates 25–35% of T-cell response to intact OVA in isolated BALB/c mouse. OVA 323-339 has been widely used to determine the characteristics of class II major histocompatibility complex (MHC)-peptide binding and T-cell activation. |
| Biochem/physiol Actions: | With the help of two functionally distinct registers ovalbumin (323-339) peptide can bind to histocompatibility complex class II I-A(d) protein. |
| General description: | Ovalbumin (323-339) is an egg white protein surrounded by B-cell epitopes, which are bound by specific IgE antibodies. In addition to this, it also contains CD4+ T cell epitopes. |
| General description: | The peptide is a major MHC class II-restricted T-cell epitope of Ovalbumin which is used for studies of immunological allergic responses such as asthma, food allergy and more.. |
| Other Notes: | Lyophilized from 0.1% TFA in H2O |
| Physical form: | Lyophilized from 0.1% aqueous TFA |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | 97-100% (HPLC) |
| Storage Temp. | −20°C |
| UNSPSC | 12352202 |