L-Ornithine monohydrochloride
SIGMA/O2375 - ≥99%
Synonym: (S)
CAS Number: 3184-13-2
Empirical Formula (Hill Notation): C5H12N2O2 · HCl
Molecular Weight: 168.62
EC Number: 221-678-6
MDL Number: MFCD00064562
Linear Formula: C5H12N2O2 · HCl
Product Type: Chemical
| application(s) | cell analysis |
| assay | ≥99% |
| color | white |
| form | powder |
| impurities | ammonia and citrulline, essentially free |
| InChI | 1S/C5H12N2O2.ClH/c6-3-1-2 |
| InChI key | GGTYBZJRPHEQDG-WCCKRBBISA |
| Quality Level | 200 ![]() |
| SMILES string | Cl.NCCC[C@H](N)C(O)=O |
| Application: | L-Ornithine monohydrochloride has been used to study the blocking effect of L-ornithine on the transport system that carries L-arginine for the overproduction of nitric oxide during lipopolysaccharide induced endotoxemia in rat model. It has also been used in decarboxylation test of amino acids. |
| Biochem/physiol Actions: | L-Ornithine is a product of arginase degradation and plays an important role in ammonia metabolism via the urea cycle. In mammals, ornithine serves as a precursor for polyamines and proline biosynthesis. Spermine synthesized from ornithine, is an abundant polyamine observed in tumors such as breast carcinomas. Administration of L-ornithine is known to improve subjective index of sleep quality. L-ornithine reduces the cortisol/DHEA-S (dehydroepiandrosterone) ratio, that is associated with stress. In mice, L-ornithine is found to affect the levels of plasma growth hormone, corticosterone and melatonin levels in mice. |
| Other Notes: | Product of arginine degradation by arginase |
| Packaging: | 1 kg in poly bottle |
| Packaging: | 10 mg in glass bottle |
| Packaging: | 5, 25, 100 g in poly bottle |
| Hazard Codes | Xi |
| Risk Statements | 36 |
| Safety Statements | 26 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥99% |
| UNSPSC | 12352209 |

