Oxytocin

SIGMA/O3251

Synonym: α-Hypophamine; Oxytocic hormone

CAS Number: 50-56-6
Empirical Formula (Hill Notation): C₄₃H₆₆N₁₂O₁₂S₂
Molecular Weight: 1007.19
EC Number: 200-048-4
MDL Number: MFCD00076731
Linear Formula: C₄₃H₆₆N₁₂O₁₂S₂
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-O3251-500IU	500 I.U.	$68.60 1/EA		Add To Favorites
45-O3251-1000IU	1000 I.U.	$118.00 1/EA		Add To Favorites
45-O3251-5000IU	5000 I.U.	$492.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥97% (HPLC)
biological source	synthetic (organic)
form	lyophilized powder
InChI	1S/C43H66N12O12S2/c1-5-22(4)35-42(66)49-26(12-13-32(45)57)38(62)51-29(17-33(46)58)39(63)53-30(20-69-68-19-25(44)36(60)50-28(40(64)54-35)16-23-8-10-24(56)11-9-23)43(67)55-14-6-7-31(55)41(65)52-27(15-21(2)3)37(61)48-18-34(47)59/h8-11,21-22,25-31,35,56H,5-7,12-20,44H2,1-4H3,(H2,45,57)(H2,46,58)(H2,47,59)(H,48,61)(H,49,66)(H,50,60)(H,51,62)(H,52,65)(H,53,63)(H,54,64)/t22-,25-,26-,27-,28-,29-,30-,31-,35-/m0/s1
InChI key	XNOPRXBHLZRZKH-DSZYJQQASA-N
Quality Level	200
shipped in	ambient
SMILES string	[H]N[C@H]1CSSC[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O)[C@@H](C)CC)C(=O)N3CCC[C@H]3C(=O)N[C@@H](CC(C)C)C(=O)NCC(N)=O
sterility	non-sterile
storage temp.	2-8°C
UniProt accession no.	P01178
	P30559
	P70536

Amino Acid Sequence:	Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2 [Disulfide Bridge: 1-6]
Application:	Oxytocin has been used in experimental study to induce uterine contractions in rats. It has been used in comet assay to determine the number of cells with DNA damage.
Biochem/physiol Actions:	Oxytocin (OXT) and arginine vasopressin hormone plays a vital role in regulation of water excretion, parturition and lactation. OXT has been implicated in hydromineral homeostasis and vascular and cardiac relaxation. Oxytocin might function as an effective therapeutic for psychiatric diseases, including depression, schizophrenia, anxiety disorders and autism. OXT has a potential as a marker of autism severity. OXT is an anorexigenic neuropeptide, which is implicated in social cognition and obsessive-compulsive behavior. Plasma oxytocin levels are high in children with Prader-willi syndrome (PWS) compared with unrelated and unaffected siblings. Deficiency of OXT hormone might contribute to pathogenesis of attention deficit/hyperactivity disorder (ADHD).
Biochem/physiol Actions:	Stimulates uterine contraction and lactation; increases Na⁺ excretion; stimulates myometrial GTPase and phospholipase C.
General description:	Oxytocin (OXT) is a potent natriuretic hormone encoded by the gene mapped to human chromosome 20p13. It is synthesized along with its carrier protein neurophysin I from its inactive precursor prepro-OXT. OXT gene consists of three exons and two introns where first exon codes for hormone OXT while other exon codes for neurophysin I.
Packaging:	500, 1000, 5000 I.U. in glass bottle
Physical form:	Supplied as a powder with a peptide content of ≥ 75%

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥97% (HPLC)
Storage Temp.	2-8°C
UNSPSC	51111800

Choose a favorite list for this item:

Catalog Number	Description	Price

		$

Please choose a list :

Continue Shopping

Returns/Order support

Please fill out the form below if you want to request order support from Krackeler Scientific.