Oxcarbazepine
SIGMA/O3764 - ≥98% (HPLC), solid
Synonym: 10,11-
CAS Number: 28721-07-5
Empirical Formula (Hill Notation): C15H12N2O2
Molecular Weight: 252.27
EC Number: 249-188-8
MDL Number: MFCD00865307
Linear Formula: C15H12N2O2
Product Type: Chemical
| assay | ≥98% (HPLC) |
| color | white |
| form | solid |
| InChI | 1S/C15H12N2O2/c16-15(19)1 |
| InChI key | CTRLABGOLIVAIY-UHFFFAOYSA |
| originator | Novartis |
| Quality Level | 100  |
| SMILES string | O=C1CC2=C(C=CC=C2)N(C(N)= |
| solubility | DMSO: ~9 mg/mL |
| Application: | Oxcarbazepine has been used in reversed-phase high-performance liquid chromatography of human epileptic brain endothelial cells. |
| Biochem/physiol Actions: | Anticonvulsant, antineuralgic. Inhibits veratrine-induced transmitter release. |
| Features and Benefits: | This compound was developed by Novartis . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here . |
| General description: | Oxcarbazepine (OXC) is the keto-analog of carbamazepine. Unlike carbamazepine, oxcarbazepine has no side effects. It is an antiepileptic drug, with an antineuralgic property. It has a pharmacokinetic advantage over carbamazepine. It is prescribed for neuropathic pain and serves as an effective pain reliever in trigeminal neuralgia. The catabolism of OXC to its monohydroxy derivative has significant pharmacologic property. It modulates potassium channels and voltage-dependent sodium channels. OXC modulates V2 receptor-G protein complex in collecting tubules and is used for treating diabetes insipidus. |
| Packaging: | 10, 50 mg in glass bottle |
| Symbol |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P301 + P312 + P330 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (HPLC) |
| UNSPSC | 12352200 |