Oxaloacetic acid
SIGMA/O4126 - ≥97% (HPLC)
Synonym: 2-Oxosuccinic acid; Ketosuccinic acid; Oxalacetic acid; Oxobutanedioic acid
CAS Number: 328-42-7
Empirical Formula (Hill Notation): C4H4O5
Molecular Weight: 132.07
EC Number: 206-329-8
MDL Number: MFCD00002592
Linear Formula: HOOCCH2COCOOH
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.
This image depicts SKU: O4126-100G
This image depicts SKU: O4126-100G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.
This image depicts SKU: O4126-1G
This image depicts SKU: O4126-1G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.
This image depicts SKU: O4126-5G
This image depicts SKU: O4126-5G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.
This image depicts SKU: O4126-25G
This image depicts SKU: O4126-25G
| assay | ≥97% (HPLC) |
| form | powder |
| InChI | 1S/C4H4O5/c5-2(4(8)9)1-3( |
| InChI key | KHPXUQMNIQBQEV-UHFFFAOYSA |
| Quality Level | 200  |
| SMILES string | OC(=O)CC(=O)C(O)=O |
| solubility | H2O: 100 mg/mL, clear to slightly hazy, colorless to light yellow |
| storage temp. | −20°C |
| Application: | Oxaloacetic acid has been used as a substrate for measuring citrate synthase activity in cybrids and neuroblastoma cells. It has also been used for measuring malate dehydrogenase reactivation. |
| Biochem/physiol Actions: | Oxaloacetic acid being an intermediate in the tri carboxylic cycle is central to metabolism. It is part of gluconeogenesis pathway. Mutation in pyruvate carboxylase leads to decreased production of oxaloacetate. It inhibits succinate dehydrogenase and is a key regulator of mitochondrial metabolism. |
| General description: | Oxaloacetic acid is a dicarboxylic acid. It is an intermediate in the citric acid cycle. It is highly soluble in water and is present ubiquitously. It is produced in the mitochondria by the action of pyruvate carboxylase on pyruvate. Breakdown products of oxaloacetate includes malate, pyruvate and aspartic acid. |
| Packaging: | 1, 5, 25, 100 g in poly bottle |
| Symbol |  GHS07 |
| Signal word | Warning |
| Hazard statements | H319 |
| Precautionary statements | P264 - P280 - P305 + P351 + P338 - P337 + P313 |
| Hazard Codes | C |
| Risk Statements | 34 |
| Safety Statements | 26-36/37/39-45 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥97% (HPLC) |
| Storage Temp. | −20°C |
| UNSPSC | 12352204 |