Oxaloacetic acid
SIGMA/O7753 - powder, BioReagent, suitable for cell culture, suitable for insect cell culture, ≥97% (HPLC)
Synonym: 2-Oxosuccinic acid; Ketosuccinic acid; Oxalacetic acid; Oxobutanedioic acid
CAS Number: 328-42-7
Empirical Formula (Hill Notation): C4H4O5
Molecular Weight: 132.07
EC Number: 206-329-8
MDL Number: MFCD00002592
Linear Formula: HOOCCH2COCOOH
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: O7753-100G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: O7753-5G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: O7753-25G
| assay | ≥97% (HPLC) |
| biological source | synthetic (organic) |
| form | powder |
| InChI | 1S/C4H4O5/c5-2(4(8)9)1-3( |
| InChI key | KHPXUQMNIQBQEV-UHFFFAOYSA |
| product line | BioReagent |
| Quality Level | 200  |
| SMILES string | OC(=O)CC(=O)C(O)=O |
| solubility | H2O: 100 mg/mL |
| storage temp. | −20°C |
| technique(s) | cell culture | insect: suitable |
| cell culture | mammalian: suitable |
| Application: | Oxaloacetic acid has been used to evaluate its effect on neuromuscular function and lifespan in amyotrophic lateral sclerosis (ALS) model superoxide dismutase 1 (SOD1) G93A mice. It has also been used as a supplement in Dulbecco′s modified Eagle′s medium (DMEM) to culture chicken fibroblast (DF-1) cells and chemically immortalized leghorn male hepatoma (LMH) cells for functional validation experiments. |
| Biochem/physiol Actions: | Oxaloacetic acid plays a vital role in central metabolism. It inhibits succinate dehydrogenase and is a key regulator of mitochondrial metabolism. |
| General description: | Oxaloacetic acid is a dicarboxylic acid that is present in every cell in the body. It is a metabolic intermediate of the tricarboxylic acid (TCA) cycle and gluconeogenesis. |
| Packaging: | 5, 25, 100 g in poly bottle |
| Symbol |  GHS07 |
| Signal word | Warning |
| Hazard statements | H319 |
| Precautionary statements | P264 - P280 - P305 + P351 + P338 - P337 + P313 |
| Hazard Codes | C |
| Risk Statements | 34 |
| Safety Statements | 26-36/37/39-45 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥97% (HPLC) |
| Storage Temp. | −20°C |
| UNSPSC | 12352204 |