Oleuropein

SIGMA/O8889 - ≥80% (HPLC)

CAS Number: 32619-42-4
Empirical Formula (Hill Notation): C₂₅H₃₂O₁₃
Molecular Weight: 540.51
EC Number: 251-129-6
MDL Number: MFCD16879008
Linear Formula: C₂₅H₃₂O₁₃
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-O8889-500MG	500 mg	$550.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

application(s)	metabolomics vitamins, nutraceuticals, and natural products
assay	≥80% (HPLC)
description	Synthetic
form	powder
InChI	1S/C25H32O13/c1-3-13-14(9-19(29)35-7-6-12-4-5-16(27)17(28)8-12)15(23(33)34-2)11-36-24(13)38-25-22(32)21(31)20(30)18(10-26)37-25/h3-5,8,11,14,18,20-22,24-28,30-32H,6-7,9-10H2,1-2H3/b13-3+/t14-,18+,20+,21-,22+,24-,25-/m0/s1
InChI key	RFWGABANNQMHMZ-ZCHJGGQASA-N
Quality Level	100
SMILES string	COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)C(=CC)[C@@H]1CC(=O)OCCc3ccc(O)c(O)c3
storage temp.	room temp

Application:	Oleuropein has been used: • as an anticancer agent to test its effect on different apoptotic pathway regulators in two breast cancer cell lines (MCF7 and MDA-MB-231) in cell viability assay • as an antioxidant to test its effect on the hydrogen peroxide (H2O2)-induced premature senescence in human fibroblast cell lines • to test its anticancer properties on the cell viability, cisplatin resistance, and apoptosis in two ovarian cell lines (A2780S and A2780/CP cell lines) • as a model antioxidant to analyze the quenching activity of 2,2-diphenyl-1-picrylhydrazyl (DPPH) in different solvents
Biochem/physiol Actions:	Oleuropein has many pharmacological benefits with its antioxidant, anti-inflammatory, antimicrobial, antiviral, hypoglycemic, hypolipidemic, neuroprotective, and anti-aging effects. It has shown antimycoplasmal activity against Mycoplasma strains in in vitro studies.
Biochem/physiol Actions:	Phenolic constituent of olive oil. Contributes to anticancer properties of olive oil. Oleuropein and its metabolite, hydroxytyrosol, inhibit the rate of cancer cell proliferation and induce cancer cell apoptosis.
General description:	Oleuropein is one of the main phenolic compounds of olive oil, which gives a bitter and pungent taste to the extra-virgin olive oil. It is a type of secoiridoids and an ester of 3-Hydroxytyrosol with an oleosidic skeleton. Oleuropein is found in the oil and fruits of Olea europaea and also in genera belonging to the Oleaceae family.

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥80% (HPLC)
Storage Temp.	room temp
UNSPSC	12352200

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