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Oxatomide

SIGMA/O9387 - ≥99%

Synonym: 1-[3-[4-(Diphenylmethyl)-1-piperazinyl]propyl]-1,3-dihydro-2H-benzimidazol-2-one

CAS Number: 60607-34-3
Empirical Formula (Hill Notation): C27H30N4O
Molecular Weight: 426.55
EC Number: 262-320-9
MDL Number: MFCD00211147
Linear Formula: C27H30N4O
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-O9387-10MG 10 mg
 $357.00
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assay ≥99%
color white
form powder
InChI 1S/C27H30N4O/c32-27-28-24-14-7-8-15-25(24)31(27)17-9-16-29-18-20-30(21-19-29)26(22-10-3-1-4-11-22)23-12-5-2-6-13-23/h1-8,10-15,26H,9,16-21H2,(H,28,32)
InChI key BAINIUMDFURPJM-UHFFFAOYSA-N
originator Johnson & Johnson
Quality Level 100 
SMILES string O=C1Nc2ccccc2N1CCCN3CCN(CC3)C(c4ccccc4)c5ccccc5
solubility DMSO: soluble
  ethanol: soluble
Biochem/physiol Actions: Oxatomide is an anti-allergy compound. It suppresses platelet activating factor (PAF)-induced bronchoconstriction and inhibits leukotriene production.
Biochem/physiol Actions: Oxatomide, found in several antihistamines, can suppress mast cell degranulation. It can be used as an alternative to individuals with allergic rhinitis who do not or poorly respond to more established antihistamines. Oxatomide exhibits both antihistamine and anti-inflammatory properties. It exhibits therapeutic effects against asthma and vulvar lichen sclerosus.
Features and Benefits: This compound was developed by Johnson & Johnson . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here .
General description: Oxatomide, a histamine H1-receptor antagonist, is bound at high levels to plasma proteins in human blood.
Symbol GHS07  GHS07
Signal word Warning
Hazard statements H302
Hazard Codes Xn
Risk Statements 22
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥99%
UNSPSC 51111800

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