Orientin

SIGMA/O9765 - ≥97% (HPLC)

Synonym: 8-β-D-Glucopyranosyl-3′,4′,5,7-tetrahydroxyflavone; Luteolin 8-C-β-D-glucopyranoside; Luteolin-8-glucoside; Lutexin

CAS Number: 28608-75-5
Empirical Formula (Hill Notation): C₂₁H₂₀O₁₁
Molecular Weight: 448.38
MDL Number: MFCD00017432
Linear Formula: C₂₁H₂₀O₁₁
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-O9765-1MG	1 mg	$148.00 1/EA	Add To Favorites
45-O9765-5MG	5 mg	$547.00 1/EA	Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

application(s)	metabolomics vitamins, nutraceuticals, and natural products
assay	≥97% (HPLC)
color	yellow
form	powder
InChI	1S/C21H20O11/c22-6-14-17(28)18(29)19(30)21(32-14)16-11(26)4-10(25)15-12(27)5-13(31-20(15)16)7-1-2-8(23)9(24)3-7/h1-5,14,17-19,21-26,28-30H,6H2/t14-,17-,18+,19-,21+/m1/s1
InChI key	PLAPMLGJVGLZOV-VPRICQMDSA-N
Quality Level	100
SMILES string	OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c2c(O)cc(O)c3C(=O)C=C(Oc23)c4ccc(O)c(O)c4
solubility	1 M NaOH: 1 mg/mL, clear, yellow-orange
storage temp.	2-8°C

Application:	Orientin has been used: • as an anti-inflammatory and anti-proliferative agent to test its protective effects against 1,2-dimethyl hydrazine (DMH)-induced colorectal cancer in rats model • as a flavanoid to investigate its protective effects against mitochondrial dysfunction on antimycin-A induced murine C2C12 skeletal muscle cells • as a potential endonuclease inhibitor of influenza polymerase PA subunit
Biochem/physiol Actions:	Flavonoid glycoside found in the acai tree and globe and passion flowers. Antiviral, antimicrobial and antioxidant. Exhibits radioprotective activities.
Biochem/physiol Actions:	Orientin displays neuroprotective effects against hydrogen peroxide-induced SH-SY5Y neuroblastoma cells. It exerts antioxidant, anti-inflammation, antiaging, antidepressant-like, vasodilation, vasorelaxant, and cardioprotective effects.
General description:	Orientin (ORI) is a luteolin derivative and water soluble 8-C-glucoside dietary flavone. It has one ketone, two ether, and phenyl groups in its chemical structure. Orientin is sourced from many medicinal plants such as Ocimum sanctum (holy basil), Phyllostachys species (bamboo leaves), Passiflora species, Trollius species, etc.
Packaging:	1, 5 mg in glass bottle

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥97% (HPLC)
Storage Temp.	2-8°C
UNSPSC	12352205

To Order From a Quote