Periodic acid
SIGMA/P0430 - suitable for electrophoresis, ≥99%
Synonym: Iodic acid; Orthoperiodic acid; Paraperiodic acid
CAS Number: 10450-60-9
Empirical Formula (Hill Notation): H5IO6
Molecular Weight: 227.94
EC Number: 233-937-0
MDL Number: MFCD00011344
Linear Formula: H5IO6
Product Type: Chemical
| assay | ≥99% |
| form | powder or crystals |
| grade | electrophoresis grade |
| InChI | 1S/H5IO6/c2-1(3,4,5,6)7/h |
| InChI key | TWLXDPFBEPBAQB-UHFFFAOYSA |
| mp | 122 °C (lit.) |
| Quality Level | 100  |
| reaction suitability | reagent type: oxidant |
| SMILES string | OI(O)(O)(O)(O)=O |
| solubility | water: 100 mg/mL, clear, colorless |
| technique(s) | electrophoresis: suitable |
| Analysis Note: | Tested for use in staining of glycoproteins. |
| Application: | Periodic acid is commonly used as a component for glycoprotein stains. Selective staining of glycoproteins on SDS-PAGE and membranes is carried out using a modification of the Periodic Acid-Schiff (PAS) method. Staining of sugar moieties of glycoproteins yields magenta bands with a colorless background. The Periodic Acid/Schiff Reagent stains vicinal diol groups found mainly on peripheral sugars and sialic acids and is used as a general glycoprotein stain. Periodic acid is also used to cleave reversible cross-linkers (e.g. DATD, DHEBA) in PAGE gels. |
| Symbol |     GHS03,GHS05,GHS08,GHS09 |
| Signal word | Danger |
| Hazard statements | H271 - H314 - H372 - H410 |
| Precautionary statements | P210 - P260 - P273 - P280 - P303 + P361 + P353 - P305 + P351 + P338 |
| Hazard Codes | O,C |
| Risk Statements | 8-34 |
| Safety Statements | 17-26-36/37/39-45 |
| RIDADR | UN 3085 8(5.1) / PGII |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥99% |
| mp | 122 °C (lit.) |
| UNSPSC | 41105319 |