Pindolol

SIGMA/P0778 - ≥98% (TLC), powder

Synonym: 1-(1H-Indol-4-yloxy)-3-(isopropylamino)-2-propanol; 1-(1H-Indol-4-yloxy)-3-[(1-methylethyl)amino]-2-propanol

CAS Number: 13523-86-9
Empirical Formula (Hill Notation): C₁₄H₂₀N₂O₂
Molecular Weight: 248.32
EC Number: 236-867-9
MDL Number: MFCD00010530
Linear Formula: C₁₄H₂₀N₂O₂
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-P0778-250MG	250 mg	$107.00 1/EA	Add To Favorites
45-P0778-1G	1 g	$146.00 1/EA	Add To Favorites

This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: P0778-1G

Properties
Descriptions
Safety Info.
Basic Data

assay	≥98% (TLC)
color	white to off-white
form	powder
InChI	1S/C14H20N2O2/c1-10(2)16-8-11(17)9-18-14-5-3-4-13-12(14)6-7-15-13/h3-7,10-11,15-17H,8-9H2,1-2H3
InChI key	JZQKKSLKJUAGIC-UHFFFAOYSA-N
mp	167-171 °C (lit.)
originator	Novartis
Quality Level	200
SMILES string	CC(C)NCC(O)COc1cccc2[nH]ccc12
solubility	0.1 M HCl: 20 mg/mL
	0.1 M NaOH: 0.2 mg/mL
	45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 0.2 mg/mL
	acetic acid: 50 mg/mL
	H₂O: insoluble
storage temp.	2-8°C

Application:	Pindolol has been used in intestinal transport and metabolism assays and cassette mix preparation.
Biochem/physiol Actions:	β₁-adrenoceptor antagonist; putative 5-HT_1A serotonin receptor agonist; vasodilator.
Biochem/physiol Actions:	β1-adrenoceptor antagonist; putative 5-HT1A serotonin receptor agonist; vasodilator. Pindolol is a non-cardioselective beta-adrenergic blocking agent. It possesses intrinsic sympathomimetic activity.
Features and Benefits:	Shelf-life of the powder is at least five years.
Features and Benefits:	This compound is a featured product for ADME Tox and Neuroscience research. Discover more featured ADME Tox and Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm .
Features and Benefits:	This compound is featured on the β-Adrenoceptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
Features and Benefits:	This compound was developed by Novartis . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here .
Packaging:	1 g in poly bottle
Packaging:	250 mg in poly bottle

Symbol	GHS07
Signal word	Warning
Hazard statements	H302 - H315 - H319 - H335
Precautionary statements	P301 + P312 + P330 - P302 + P352 - P305 + P351 + P338
Hazard Codes	Xn
Risk Statements	22-36/37/38
Safety Statements	26-36
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3

Purity	≥98% (TLC)
mp	167-171 °C (lit.)
Storage Temp.	2-8°C
UNSPSC	12352200

To Order From a Quote