O-Phospho-L-serine
SIGMA/P0878
Synonym: L-
CAS Number: 407-41-0
Empirical Formula (Hill Notation): C3H8NO6P
Molecular Weight: 185.07
EC Number: 206-986-0
MDL Number: MFCD00065935
Linear Formula: (HO)2P(O)OCH2CH(NH2)CO2H
Product Type: Chemical
| form | powder |
| InChI | 1S/C3H8NO6P/c4-2(3(5)6)1- |
| InChI key | BZQFBWGGLXLEPQ-REOHCLBHSA |
| mp | 190 °C (lit.) |
| Quality Level | 200  |
| SMILES string | N[C@@H](COP(O)(O)=O)C(O)= |
| storage condition | under inert gas |
| Application: | O-Phospho- • for the expression, purification and phosphorylation of protein • to study its chemical shift • to spectroscopically determine its pKa values using Raman spectroscopy |
| Biochem/physiol Actions: | Group III metabotropic glutamate receptor agonist (mGluR4, mGluR7, and mGluR8). |
| Biochem/physiol Actions: | O-Phospho-L-serine (L-SOP) is a molecule which resembles phosphatidylserine head group and it mediates partial inhibition of microglial phagocytosis of apoptotic cells. In zebrafish, L-SOP inhibits Müller glia proliferation and blocks cone cell regeneration in the light-damaged retina. In vivo, L-SOP acts as a substrate for CysM, a cysteine synthase from Mycobacterium tuberculosis. |
| Packaging: | 10 mg in autosample vial |
| Symbol |  GHS05 |
| Signal word | Danger |
| Hazard statements | H314 |
| Precautionary statements | P260 - P280 - P301 + P330 + P331 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 |
| RIDADR | UN 3261 8 / PGII |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| mp | 190 °C (lit.) |
| UNSPSC | 12352209 |