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Paroxetine maleate salt

SIGMA/P1372 - ≥98% (HPLC), solid

Synonym: (3S-trans)-3-[(1,3-Benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine maleate salt; BRL-29060; FG-7051

CAS Number: 64006-44-6
Empirical Formula (Hill Notation): C19H20FNO3 · C4H4O4
Molecular Weight: 445.44
MDL Number: MFCD01742665
Linear Formula: C19H20FNO3 · C4H4O4
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-P1372-10MG 10 mg
 $178.00
1/EA		 Add To Favorites
45-P1372-50MG 50 mg
 $702.00
1/EA		 Add To Favorites

 

assay ≥98% (HPLC)
color white to off-white
form solid
InChI 1S/C19H20FNO3.C4H4O4/c20-15-3-1-13(2-4-15)17-7-8-21-10-14(17)11-22-16-5-6-18-19(9-16)24-12-23-18;5-3(6)1-2-4(7)8/h1-6,9,14,17,21H,7-8,10-12H2;1-2H,(H,5,6)(H,7,8)/b;2-1-/t14-,17-;/m0./s1
InChI key AEIUZSKXSWGSRU-QXGDPHCHSA-N
originator GlaxoSmithKline
Quality Level 100 
SMILES string OC(=O)C=C/C(O)=O.Fc1ccc(cc1)[C@@H]2CCNC[C@H]2COc3ccc4OCOc4c3
solubility DMSO: ~12 mg/mL
  H2O: insoluble
storage temp. 2-8°C
Biochem/physiol Actions: Paroxetine is a strong cytochrome P450 2D6 isotype (CYP2D6) inhibitor, which reduces the effectiveness of tamoxifen. This phenylpiperidine derivative inhibits clozapine metabolism. Paroxetine is used to treat social phobia, obsessive-compulsive disorder and panic disorder. It is also used to treat the premenstrual dysphoric disorder, post-traumatic stress disorder and chronic headache.
Biochem/physiol Actions: Paroxetine maleate is a selective serotonin reuptake inhibitor; antidepressant.
Features and Benefits: This compound is featured on the Biogenic Amine Transporters  page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
Features and Benefits: This compound was developed by GlaxoSmithKline . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here .
Legal Information: Sold with the permission of Glaxo­Smith­Kline
Packaging: 10, 50 mg in glass bottle
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

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