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Pterostilbene

SIGMA/P1499 - ≥97% (HPLC), solid

Synonym: Pterocarpus marsupium; 3,5-Dimethoxy-4′-hydroxystilbene; 4-[(1E)-2-(3,5-Dimethoxyphenyl)ethenyl]phenol

CAS Number: 537-42-8
Empirical Formula (Hill Notation): C16H16O3
Molecular Weight: 256.30
MDL Number: MFCD00238710
Linear Formula: C16H16O3
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-P1499-10MG 10 mg
 $317.00
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assay ≥97% (HPLC)
form solid
InChI 1S/C16H16O3/c1-18-15-9-13(10-16(11-15)19-2)4-3-12-5-7-14(17)8-6-12/h3-11,17H,1-2H3/b4-3+
InChI key VLEUZFDZJKSGMX-ONEGZZNKSA-N
Quality Level 100 
SMILES string COc1cc(OC)cc(C=Cc2ccc(O)cc2)c1
solubility DMSO: >20 mg/mL
  H2O: insoluble
storage condition protect from light
storage temp. 2-8°C
Application: Pterostilbene has been used:
• to investigate its anti-oxidative stress activities and the involvement of the nuclear factor (erythroid-derived 2)-like 2 (Nrf2)-antioxidant response element (ARE) signaling pathway
• to determine its effects on transcriptional activation of estrogen receptor-α (ERα) in hormone resistant breast cancer cells)
• to study its effects on the cytotoxicity of 2-chloroethyl ethyl sulphide (CEES) in human epidermoid carcinoma cells (A-431) through MTT (3-[4,5-dimethylthiazol-2-yl]-2,5 diphenyl tetrazolium bromide)viability assay
Biochem/physiol Actions: Antioxidant, antiproliferative, apoptosis inducer, antihyperglycemic, antidiabetic.
Biochem/physiol Actions: Pterostilbene exhibits antineoplastic properties in some of the malignancies, hence it is considered as an active anticancer agent. It has the ability to stimulate apoptosis and block the viability of cell in estrogen-receptor positive and negative breast cancer cell lines.
Disclaimer: Air-sensitive
General description: Pterostilbene (trans-3,5-dimethoxy-4-hydroxystilbene), an antioxidant is an analogue of resveratrol. It is present in blueberries, tree wood and some types of grapes.
Packaging: 10 mg in glass bottle
Purity ≥97% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

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