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Patulin

SIGMA/P1639 - ≥98.0% (HPLC)

Synonym: Clavacin; Clavatin; Expansine; Gigantin; Leucopin; Mycoine C3; Terinin; 4-Hydroxy-4H-furo[3,2-c]pyran-2(6H)-one

CAS Number: 149-29-1
Empirical Formula (Hill Notation): C7H6O4
Molecular Weight: 154.12
EC Number: 205-735-2
MDL Number: MFCD00005858
Linear Formula: C7H6O4
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-P1639-5MG 5 mg
 $207.00
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45-P1639-10MG 10 mg
 $384.00
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45-P1639-25MG 25 mg
 $801.00
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This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: P1639-10MG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: P1639-25MG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: P1639-5MG

 

antibiotic activity spectrum fungi
assay ≥98.0% (HPLC)
form powder
InChI 1S/C7H6O4/c8-6-3-4-5(11-6)1-2-10-7(4)9/h1,3,7,9H,2H2
InChI key ZRWPUFFVAOMMNM-UHFFFAOYSA-N
mode of action cell membrane | interferes
Quality Level 300 
SMILES string OC1OCC=C2OC(=O)C=C12
solubility water: 9-11 mg/mL
storage temp. −20°C
Application: Patulin has been used:
• to study patulin contamination of bottled wine
• in DNA-damaging activity of patulin in Escherichia coli
• in molecular cloning and functional characterization of two CYP619 cytochrome P450s involved in biosynthesis of patulin in Aspergillus clavatus
Biochem/physiol Actions: Mycotoxin with anti-bacterial, potassium uptake inhibitory, and possibly carcinogenic activities. It is used as an inhibitor of potassium uptake and as an inducer of ion flux across cell membranes, potentially involving Na+-K+ dependent ATPase and to induce intra- and intermolecular protein crosslinking.
General description: Patulin is a mycotoxin produced by a variety of molds, such as, Aspergillus and Penicillium. It is commonly found in apples. It is used as an inhibitor of potassium uptake and as an inducer of ion flux across cell membranes, potentially involving Na+-K+ dependent ATPase and to induce intra- and intermolecular protein crosslinking.
Other Notes: Keep container tightly closed in a dry and well-ventilated place.
Packaging: 5, 10, 25 mg in glass bottle
Purity ≥98.0% (HPLC)
Storage Temp. −20°C
UNSPSC 51102829

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