Prealbumin from human plasma
SIGMA/P1742 - lyophilized powder
Synonym: Thyroxine binding prealbumin; Transthyretin
CAS Number: 87090-18-4
MDL Number: MFCD00132069
Product Type: Chemical
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| ε (extinction coefficient) | 13.5 at 280 nm at 1% |
| assay | ≥95% (SDS-PAGE) |
| biological source | human plasma |
| form | lyophilized powder |
| impurities | Infectious agents, tested |
| Quality Level | 200  |
| solubility | H2O: soluble 1 mg/mL |
| storage temp. | −20°C |
| technique(s) | immunoelectrophoresis: suitable |
| immunoprecipitation (IP): suitable | |
| UniProt accession no. | P02766  |
| Application: | Human prealbumin was used to study reduced transthyretin expression in sera of lung cancer. |
| Application: | Prealbumin from human plasma has been used as a positive control in immunoprecipitation as a reference standard in quantitative rocket immunoelectrophoresis for quantification of cerebrospinal fluid. |
| Biochem/physiol Actions: | Human prealbumin has been observed in carcinoid tumors. |
| Biochem/physiol Actions: | Prealbumin levels are indictors of malnutrition and may be modulated during inflammation. It is regarded as potential marker of protein energy malnutrition (PEM) during chronic kidney failure supported dialysis. Low levels of prealbumin poses high risk to heart failure (HF). |
| General description: | Human prealbumin is a product of chromosome 18. It is a serum protein, synthesized primarily in the liver. It is a tetrameric protein with a molecular weight of 55 kDa. Human prealbumin is composed of four identical non-covalently bound monomers of 127 amino acid residues arranged with tetrahedral symmetry. |
| Packaging: | Package size based on protein content |
| Physical form: | Lyophilized powder containing sodium phosphate and NaCl |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥95% (SDS-PAGE) |
| Storage Temp. | −20°C |
| UNSPSC | 12352202 |